Methods of using adipose derived stem cells to promote wound healing

Patent Citations (150)

Non-Patent Literature (522)

• Tosh D et al. 2002. Conversion of pancreatic cells to hepatocytes. Biochem Soc Trans 30: 51-55.Examiner
• Castro RF et al. 2002. Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science 297: 1299.Examiner
• Mezey E et al. and Castro RF et al. 2003. “Comment on Failure of bone marrow cells to transdifferentiate into neural cells invivo”, “Response to Comment on Failure of bone marrow cells to trarlsdifferentiate into neural cells in vivo.” Science299:1184b,c.Examiner
• Fraser JK. Adipose Tissue: Challenging the Marrow Monopoly. Cytotherapy. 4(6):509-510 (2002).Applicant
• Gimble etal. “Adipose-Derived Adult Stem Cells: Isolation, Characterization, and Differentiation Potential.” Cytotherapy. 5(5):362-369 (2003).Applicant
• Hamano et al. The induction of angiogenesis by the implantation of autologous bone marrow cells: A novel and simple therapeutic method. Surgery. 130(1):44-54 (2001).Applicant
• Kang et al. “Improvement of neurological deficits by intracerebral transplantation of human adipose tissue-derived stromal cells after cerebral ischemia in rats.” Experimental Neurology. 183(2):355-366 (2003).Applicant
• Kang et al. “Interactions between human adipose stromal cells and mouse neural stem cells in vitro.” Developmental Brain Research. 145(1): 141-149 (2003).Applicant
• Muller et al. “Selection of ventricular-like cardiomyocytes from ES cells in vitro.” The FASEB Journal. 14:2540-2548 (2000).Applicant
• Rehman, et al. “Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells.” Circulation. 109(10):1292-1298 (2004).Applicant
• Savitz et al. “Cell Transplantation for stroke.” Annals of Neurology. 52(3):266-275 (2002).Applicant
• Supplemental European Search Report for European Application No. EP 04777546 dated Jun. 10, 2009.Applicant
• U.S. Appl. No. 09/936,665, filed Sep. 10, 2001, Katz et al., Adipose-Derived Stem Cells and Lattices.Applicant
• U.S. Appl. No. 09/952,522, filed Sep. 10, 2001, Katz et al., Adipose-Derived Stem Cells and Lattices.Applicant
• Avital, I., D. Inderbitzin, et al. (2001). “Isolation, characterization, and transplantation of bone marrow-derived hepatocyte stem cells.” Biochem Biophys Res Commun 288(1): 156-64.Applicant
• Carmeliet, P. and A. Luttun (2001). “The emerging role of the bone marrow-derived stem cells in (therapeutic) angiogenesis.” Thromb Haemost 86(1): 289-97.Applicant
• Castro-Malaspina, H., W. Ebell, et al. (1984). “Human bone marrow fibroblast colony-forming units (CFU-F).” Prog Clin Biol Res 154: 209-36.Applicant
• Coleman, S. R. (1995). “Long-term survival of fat transplants: controlled demonstrations.” Aesthetic Plast Surg 19(5): 421-5.Applicant
• Coleman, S. R. (2001). “Structural fat grafts: the ideal filler?” Clin Plast Surg 28(1): 111-9.Applicant
• Coleman, W. P., 3rd (1991). “Autologous fat transplantation.” Plast Reconstr Surg 88(4): 736.Applicant
• Connolly, J. F. (1998). “Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis.” Clin Orthop(355 Suppl): S257-66.Applicant
• Eremia, S. and N. Newman (2000). “Long-term follow-up after autologous fat grafting: analysis of results from 116 patients followed at least 12 months after receiving the last of a minimum of two treatments.” Dermatol Surg 26(12): 1150-8.Applicant
• Fukuda, K. (2001). “Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering.” Artif Organs 25(3): 187-93.Applicant
• Guerrerosantos, J., A. Gonzalez-Mendoza, et al. (1996). “Long-term survival of free fat grafts in muscle: an experimental study in rats.” Aesthetic Plast Surg 20(5): 403-8.Applicant
• Horwitz, E. M., D. J. Prockop, et al. (1999). “Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta.” Nat Med 5(3): 309-13.Applicant
• Horwitz, E. M., D. J. Prockop, et al. (2001). “Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta.” Blood 97(5): 1227-31.Applicant
• Huang, J. I., S. R. Beanes, et al. (2002).“Ratextramedullary adipose tissue as a source of osteochondrogenic progenitor cells.” Plast Reconstr Surg 109(3): 1033-41; discussion 1042-3.Applicant
• Hutley, L. J., A. C. Herington, et al. (2001). “Human adipose tissue endothelial cells promote preadipocyte proliferation.” Am J Physiol Endocrinol Metab 281(5): E1037-44.Applicant
• Kern, P. A., A. Knedler, et al. (1983). “Isolation and culture of microvascular endothelium from human adipose tissue.” J Clin Invest 71(6): 1822-9.Applicant
• Lee, J. H., Z. Ilic, et al. (1996). “Cell kinetics of repair after allyl alcohol-induced liver necrosis in mice.” Int J Exp Pathol 77(2): 63-72.Applicant
• Lee, P. E., R. C. Kung, et al. (2001). “Periurethral autologous fat injection as treatment for female stress urinary incontinence: a randomized double-blind controlled trial.” J Urol 165(1): 153-8.Applicant
• Mizuno, H., P. A. Zuk, et al. (2002). “Myogenic differentiation by human processed lipoaspirate cells.” Plast Reconstr Surg 109(1): 199-209; discussion 210-1.Applicant
• Murayama, T., O. M. Tepper, et al. (2002). “Determination of bone marrow-derived endothelial progenitor cell significance in angiogenic growth factor-Induced neovascularization in vivo.” Exp Hematol 30(8): 967-72.Applicant
• Murry, C. E., R. W. Wiseman, et al. (1996). “Skeletal myoblast transplantation for repair of myocardial necrosis.” J Clin Invest 98(11): 2512-23.Applicant
• Muschler, G. F., H. Nitto, et al. (2001). “Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors.” J Orthop Res 19(1): 117-25.Applicant
• Nishimori, M., Y. Yamada, et al. (2002). “Health-related quality of life of unrelated bone marrow donors in Japan.” Blood 99(6): 1995-2001.Applicant
• Orlic, D., J. Kajstura, et al. (2001). “Transplanted adult bone marrow cells repair myocardial infarcts in mice.” Ann N Y Acad Sci 938: 221-9; discussion 229-30.Applicant
• Orlic, D., J. Kajstura, et al. (2001). “Bone marrow cells regenerate infarcted myocardium.” Nature 410(6829): 701-5.Applicant
• Palma, P. C., C. L. Riccetto, et al. (1997). “Repeated lipoinjections for stress urinary incontinence.” J Endourol 11(1): 67-70.Applicant
• Pittenger, M. F., A. M. Mackay, et al. (1999). “Multilineage potential of adult human mesenchymal stem cells.” Science 284(5411): 143-7.Applicant
• Prockop, D. J., S. A. Azizi, et al. (2000). “Potential use of marrow stromal cells as therapeutic vectors for diseases of the central nervous system.” Prog Brain Res 128: 293-7.Applicant
• Rajnoch, C., J. C. Chachques, et al. (2001). “Cellular therapy reverses myocardial dysfunction.” J Thorac Cardiovasc Surg 121(5): 871-8. t&artType=abs&id=a112937&target=.Applicant
• Shi, Q., S. Rafii, et al. (1998). “Evidence for circulating bone marrow-derived endothelial cells.” Blood 92(2): 362-7.Applicant
• Strauer, B. E., M. Brehm, et al. (2002). “Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans.” Circulation 106(15): 1913-8.Applicant
• Takahashi, T., C. Kalka, et al. (1999). “Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization.” Nat Med 5(4): 434-8.Applicant
• Thomas, E. D. (1994). “Stem Cell Transplantation: Past, Present and Future.” Stem Cells 12: 539-544.Applicant
• Werlich, T., K. J. Stiller, et al. (1999). “Experimental studies on the stem cell concept of liver regeneration. II.” Exp Toxicol Pathol 51(1): 93-8.Applicant
• Yavorkovsky, L., E. Lai, et al. (1995). “Participation of small intraportal stem cells in the restitutive response of the liver to periportal necrosis induced by allyl alcohol.” Hepatology 21(6): 1702-12.Applicant
• Yin, L., D. Lynch, et al. (1999). “Participation of different cell types in the restitutive response of the rat liver to periportal injury induced by allyl alcohol.” J Hepatol 31(3): 497-507.Applicant
• Zuk, P. A., M. Zhu, et al. (2001). “Multilineage cells from human adipose tissue: implications for cell- based therapies.” Tissue Eng 7(2): 211-28.Applicant
• Considine, et al., “Paracrine stimulation of preadipocyte-enriched cell cultures by mature adipocytes,” American Journal of Physiology 1996 270(5) E895-E899 (Exhibit 6).Applicant
• Dani, et al., “Differentiation of embryonic stem cells into adipocytes in vitro,”J.Cell Sci. 1997 110, 1279-1285 (Exhibit 7).Applicant
• Entenmann, et al., “Relationship between replication and differentiation cultured human adipocyte precursor cells,” American Phys.Soc. 1996 270,C1011-C1016 (Exhibit 8).Applicant
• Eslami Varzaneh, et al., “Extracellular Matrix Components Secreted by Microvascular Endothelial Cells Stimulate Preadipocyte Differentiation In Vitro,” Metabolism 1994 43 (7), 906-912 (Exhibit 9).Applicant
• Hauner, et al., “Endothelin-1 Inhibits the Adipose Differentiation of Cultured Human Adipocyte Precursor Cells,” Metabolism 1994 43(2) pp. 227-232 (Exhibit 10).Applicant
• Hausman, et al., “The Influence of Extracellular Matrix Substrata on Preadipocyte Development in Serum-Free Cultures of Stromal-Vascular Cells,” J. Anim.Sci. 1996 74(9), 2117-2128 (Exhibit 11).Applicant
• Hui-Ling et al., “Increased expression of G in mouse embryo stem cells promotes terminal differentiation to adipocytes,” American Physiological Society 1993 265(6), C1729-C1735 (Exhibit 12).Applicant
• Marko, et al., “Isolation of a Preadipocyte Cell Line from Rat Bone Marrow and Differentiation to Adipocytes,” Endocrinology 1995 136(10), 4582-4588 (Exhibit 13).Applicant
• Shillabeer, et al., “A novel method for studying preadipocyte differentiation in vitro,” Intl. J. Obesity 1996 20(Supp. 3), S77-S83 (Exhibit 14).Applicant
• Sorisky et al., “From preadipocyte to Adipocyte: Differentiation-Directed Signals of Insulin from the Cell Surface to the Nucleus,” Critical Review in Clinical Laboratory Sciences 1999 36(1), 1-34 (Exhibit 15).Applicant
• Vassaux, et al., “Proliferation and differentiation of Rat Adipose Precursor Cells in Chemically Defined Medium: Differential Action of Anti-Adipogenic Agents,” Journal of Cellular Physiology 1994 161(2), 249-256 (Exhibit 16).Applicant
• Wabitsch, et al., “Biological Effects of Human Growth Hormone in Rat Adipocyte Precursor Cells and Newly Differentiated Adipocytes in primary Culture,” Metabolism 1996 vol. 45,No. 1 pp. 34-42 (Exhibit 17).Applicant
• Young et al., “Mesenchymal Stem Cells Reside Within the Connective Tissues of Many Organs,” Developmental Dynamics 1995 202(2), 137-144 (Exhibit 18).Applicant
• Bennett, JH, et al., 1991 J. Cell Sci. “Adipocytic cells cultured from marrow have osteogenic potential,” 99(Pt1):131-139 (Exhibit 26).Applicant
• Beresford, et al., 1986 Endo. “1,25- Dihydroxyvitamin D3 and Human Bone-Derived Cells in Vitro: Effects on Alkaline Phosphatase, Type I Collagen and Proliferation,” 119:1776-1785 (Exhibit 27).Applicant
• Bjornson, et al., 1999 Science “Turning Brain into Blood: A Hematopoetic Fate Adopted by Adult Neural Stem Cells in Vivo,” 283:534-537 (Exhibit 28).Applicant
• Bruder, et al., 1997 J. Cell Biochem. “Growth Kinetics, Self-Renewal, and the Osteogenic Potential of Purified Human Mesenchymal Stem Cells During Extensive Subcultivation and Following Cryopreservation,” 64:278-294 (Exhibit 29).Applicant
• Butler-Browne, et al., 1990 Anat. Embryol. (Berl) “Myosin heavy and light chain expression during human skeletal muscle development and precocious muscle maturation induced by thyroid hormone,” 181:513-522 (Exhibit 30).Applicant
• Cheng S-L., et al., 1994 Endo “Differentiation of Human Bone Marrow Osteogenic Stromal Cells in Vitro: Induction of the Osteoblast Phenotype by Dexamethasone,” 134: 277-286 (Exhibit 31).Applicant
• Chyun, et al., 1984 Endo. “Cortisol Decreases Bone Formation by Inhibiting Periosteal Cell Proliferation,” 114:477-480 (Exhibit 32).Applicant
• Conget, PA and JJ Minguell 1999 J. Cell. Physiol “Phenotypical and Functional Properties of Human Bone Marrow Mesenchymal Progenitor Cells,” 181:67-73 (Exhibit 33).Applicant
• Cooper, et al., 1999 J. Endocrinol. “Glucocorticoid activity, inactivity and the osteoblast,” 163:159-164 (Exhibit 34).Applicant
• Denker, A.E., et al., 1995 Differentiation “Formation of cartilage-like spheroids by micromass cultures of murine C3H101/2 cells upon treatment with transforming growth factor-β1,” 59: 25-34 (Exhibit 35).Applicant
• Denker, et al., 1999 Differentiation “Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures,” 64:67-76 (Exhibit 36).Applicant
• Dimri, et, al., 1995 Proc. Natl Acad. Sci. USA “A biomarker that identifies a senescent human cells in culture and in aging skin in vivo,” 92: 9363-9367 (Exhibit 37).Applicant
• Ducy, et, al., 1997 Cell “Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation,” 89:747-754 (Exhibit 38).Applicant
• Ferrari G., et al., 1998 Science “Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors,” 279: 1528-1530 (Exhibit 39).Applicant
• Frederikson and McKay 1988 J. Neurosci. “Proliferation and Differentiation of Rat Neuroepithelial Precursor Cells in vivo,” 8:1144-1151 (Exhibit 40).Applicant
• Fridman, et al., 1992 Int. J. Cancer “Malignant Transformation of NIH-3T3 Cells After Subcutaneous co-Injection With a Reconstituted Basement Membrane (Matrigel),” 51(5), 740-44 (Exhibit 41).Applicant
• Grigoradis A., et al., 1988 J. Cell Biol. “Differentiation of Muscle, Fat, Cartilage, and Bone from Progenitor Cells Present in a Bone-derived Clonal Cell Population: Effect of Dexamethasone,” 106: 2139-2151(Exhibit 42).Applicant
• Guerriero, V and JR Florini 1980 Endocrinology “Dexamethasone Effects on Myoblast Proliferation and differentiation.” 106:1198-1202(Exhibit 43).Applicant
• Hall, BK 1981 “Intracellular and extracellular control of differentiation of cartilage and bone,” Histochem. J. 13:599-614(Exhibit 44).Applicant
• Jaiswal, et al., 1997 “Osteogenic Differentiation of Purified, Culture-Expanded Human Mesenchymal Stem Cells In Vitro,” J. Cell Biochem. 64:295-312(Exhibit 45).Applicant
• Johnstone B., et al., 1998 “In Vitro Chondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells,” Exp. Cell Res. 238: 265-272(Exhibit 46).Applicant
• Kania, et al., 1990 “The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system,” Genes Dev. 4:1701-1713(Exhibit 47).Applicant
• Kehlen, A. et al., 2000 J. Cell Biochem. “Increased Lymphocytic Aminopeptidase N/CD13 Promoter Activity After Cell-Cells Contact,” 80:115-123(Exhibit 48).Applicant
• Kosher, RA, et al., 1986 J. Cell Biol. “Collagen Gene Expression During Limb Cartilage Differentiation,” 102:1151-1156(Exhibit 49).Applicant
• Kuri-Harcuch, W. et al., 1984, Differentiation “Extracellular matrix production by mouse 3T3-F442A cells during adipose differentiation in culture,” 28(Exhibit 50).Applicant
• Lanier, L.L. et al, 1991 J. Immunol. “Molecular and Functional Analysis of Human Natural Killer Cell-Associated Neural Cells Adhesion Molecule (N-Cam/CD56),”146:4421-4426(Exhibit 51).Applicant
• Lawson-Smith, M.J. and McGeachie, J.K. 1998 J. Anat. “The identification of myogenic cells in skeletal muscle, with emphasis on the use of tritiated thymidine autoradiography and desmin antibodies,” 192:161-171 (Exhibit 52).Applicant
• Leboy, et al., 1991 J. Cell Physiol. “Dexamethasone Induction of Osteoblast mRNAs in Rat Marrow Stromal Cell Cultures,” 146:370-378 (Exhibit 53).Applicant
• Lendahl, et al., 1990 Cell “CNS Stem Cells Express a New Class of Intermediate Filament Protein,” 60:585-595 (Exhibit 54).Applicant
• Lenoir, N. 2000 Science “Europe Confronts The Embryonic Stem Cell Research Challenge,” 287:1425-1427 (Exhibit 55).Applicant
• Lumelsky, N., et al. 2001 Science “Differentiation of Embryonic Stem Cells to Insulin-Secreting Structures Similar to Pancreatic Islets,” 292:1389-1394. (Exhibit 56).Applicant
• Lynch, et al., 1995, Exp. Cell Res. “The Influence of Type I Collagen on the Development and Maintenance of the Osteoblast Phenotype in Primary and Passaged Rat Calvarial Osteoblasts: Modification of Expression of Genes Supporting Cell Growth, Adhesion, and Extracelluar Matrix Mineralization,” 216:35-45 (Exhibit 57).Applicant
• Malaval, et al., 1994 J. Cell. Physiol. “Cellular Expression of Bone-Related Proteins During In Vitro Ostegenesis in Rat Bone Marrow Stromal Cell Culture,” 158:555-572 (Exhibit 58).Applicant
• Manduca, et al., 1992 Eur. J. Cell Biol. “Chondrogenic differentiation in chick embryo osteoblast cultures,” 57:193-201 (Exhibit 59).Applicant
• Martin, et al., 1999 Exp. Cell Res. “Mammalian Chondrocytes Expanded in the Presence of Fibroblast Growth Factor 2 Maintain the Ability to Differentiate and Regenerate Three-Dimensional Cartilaginous Tissue,” 253:681-688 (Exhibit 60).Applicant
• Megeney, et al., 1996 Genes Dev. “MyoD is required for myogenic stern cell function in adult skeletal muscle,” 10:1173-1183 (Exhibit 61).Applicant
• Molkentin and Olson 1996 Curr. Opin. Genet. Dev. “Defining the regulatory networks for muscle development,” 6:445-453 (Exhibit 62).Applicant
• Mundlos, et al., 1997 Cell “Mutations Involving the Transcription Factor CBFAI2 Cause Cleidocranial Dysplasia,” 89:773-779 (Exhibit 63).Applicant
• Nehls, A. and D Drenckhahn 1991 J. Cell Biol. “Heterogeneity of Microvascular Pericytes for Smooth Muscle Type Alpha-Actin,” 113:147-154 (Exhibit 64).Applicant
• Owen, Ta, et al., 1990 J. Cell Physiol. “Progressive Development of the Rat Osteoblast Phenotype in Vitro: Reciprocal Relationships in Expression of Genes Associated with Osteoblast Proliferation and Differentiation During Formation of the Bone Extracellular Matrix,” 143:420-430 (Exhibit 65).Applicant
• Paul S.R., et al., 1991 Blood “Stromal Cell-Associated Hematopoiesis: Immortalization and Characterization of Primate Bone Marrow-Derived Stromal Cell Line,” 77: 1723-33 (Exhibit 66).Applicant
• Pittenger M.F., et al., 1999 Science “Multilineage Potential of Adult Human Mesenchymal Stem Cells,” 284: 143-147 (Exhibit 67).Applicant
• Prockop D.J. 1997 Science “Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues,” 276: 71-74 (Exhibit 68).Applicant
• Rando, et al., 1995 Exp. Cell Res. “The Fate of Myoblasts Following Transportation into Mature Muscle,” 220:383-389 (Exhibit 69).Applicant
• Saalbach, A., et al., 1997 Cell and Tiss. Res. “The Fibroblast-specific MAb AS02: a novel tool for detection and elimination of human fibroblasts,” 290:593-599 (Exhibit 70).Applicant
• Sanchez-Ramos, et al., 2000 “Adult Bone Marrow Stromal Cells Differentiate into Neural Cells in Vitro,” Exp. Neurol. 164:247-256 (Exhibit 71).Applicant
• Seale and Rudnicki 2000 Dev. Biol. “A New Look at the Origin, Function, and “Stem-Cell” Status of Muscle Satellite Cells,” 218:115-124 (Exhibit 72).Applicant
• Shukunami, C., et al., 1998 Exp. Cell Res. “Sequential Progression of the Differentiation Program by Bone Morphogenetic Protein-2 in Chondrogenic Cell Line ATDC5,” 241:1-11 (Exhibit 73).Applicant
• Shukunami C., et. al., 1996 Journ. of Cell Bio. “Chrondrogenic Differentiation of Clonal Mouse Embryonic Cell Line ATDC5 In Vitro: Differentiation-dependent Gene Expression of Parathyroid Hormone (PTH)/PTH-related Peptide Receptor,” 133:2:457-468 (Exhibit 74).Applicant
• Silberstein, L., et al., 1986 Cell “Developmental Progression of Myosin Gene Expression in Cultured Muscle Cells,” 46:1075-1081 (Exhibit 75).Applicant
• Suga, S., et al., 1996, Eur. J. Cell Biol. Intracellular localization of antigens recognized by anti-vimentin monoclonal antibodies (mAbs): Cross-reactivities of anti-vimentin mAbs with other cellular components 70:84-91 (Exhibit 76).Applicant
• Tacchetti. C, et al., 1992 Exp Cell Res. “Cell Condensation in Chondrogenic Differentiation,” 200:26-33 (Exhibit 77).Applicant
• Tapscott, et al., 1988 Science “MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts,” 242:405-411 (Exhibit 78).Applicant
• Thornell, et al., 1984 J. NeuroL Sci. “Development of Fiber Types in Human Fetal Muscle,” 66:107-115 (Exhibit 79).Applicant
• Totonoz, et al., 1995 Nucl. Acid Res “mPPARγ2: tissue-specific regulator of an adipocyte enhancer,” (Exhibit 80).Applicant
• Tsonis and Goetinck 1990 Exp. Cell Res. “Cell Density Dependent Effect of a Tumor Promoter on Proliferation and Chondrogenesis of Limb Bud Mesenchymal Cells,” 190:247-253 (Exhibit 81).Applicant
• von der Mark, et al., 1977 Nature “Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture,” 267:531-532 (Exhibit 82).Applicant
• Vukicevic et al., 1992 Exp. Cell Res “Identification of Multiple Active Growth factors in Basement Membrane Matrigel Suggests Caution in Interpretation of Cellular Activity Related to Extracellular Matrix Components,”, 202(1), 1-8 (Exhibit 83).Applicant
• Weintraub, et al., 1991 Science “The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage,” 251:761-766 (Exhibit 84).Applicant
• Woodbury, et al., 2000 J. Neurosci. Res. Science “Adult Rat and Human Bone Marrow Stromal cells Differentiate Into Neurons,” 61:364-370 (Exhibit 85).Applicant
• Young, 2000 Science “A Time for Restraint,” 287:1424. (Exhibit 86).Applicant
• Zalin, RJ 1987 Exp. Cell Res. “The Role of Hormones and Prostanoids in the in Vitro Proliferation and differentiation of Human Myoblasts,” 172:265-281. (Exhibit 87).Applicant
• Ankrom, Michael A., “Age-related changes in human oestrogen receptor function and levels in osteoblasts,” Biochem J. 333:787-794. (Exhibit 88).Applicant
• Aso, Hisashi, et al., “A Preadipocyte Clonal Line from bovine Intramuscular Adipose Tissue: Nonexpression of GLUT-4 protein during Adipocyte Differentiation,” Biochem. Biophys. Res. Commun. 213:369-375. (Exhibit 89).Applicant
• Bernlohr, David A. et al., “Tissue Specific Expression of p422 protein , A putative Lipid Carrier, in Mouse Adipocytes,” Biochem. Biophys. Res. Comun. 1985 132:850-855. (Exhibit 90).Applicant
• Cheifetz, S. et al., “Endoglin Is a Component of the Transforming Growth Factor-β Receptor System in Human Endothelial Cells,” J. Biol. Chem., 1992 267:19027-19030. (Exhibit 91).Applicant
• Chen, Theresa L. et al., “1α,25-Dihydroxyvitamin D3 Receptors in Cultured Rat osteoblast-like Cells,” J. Biol. Chem. 1983 258:4350-4355. (Exhibit 92).Applicant
• Enomoto, Hiroyuki et al., “Cbfal Is a Positive Regulatory Factor in Chondrocyte Maturation,” J. Biol. Chem. 2000 275:8695-8702. (Exhibit 93).Applicant
• Herman, Ira M. and Patricia D'Amore, “Microvascular Pericytes Contain Muscle and Nonmuscle Actins,” J. Cell Biol. 1985 101:43-52. (Exhibit 94).Applicant
• Lucas, Paul A. et al., “Mesenchymal Stem Cells From Granulation Tissue,” J. Cell Biochem, 1993 17E:122, R212 (Exhibit 95).Applicant
• Majeska, Robert J. and Gideon A. Rodan, “The Effect of 1,25(OH)2D3 on Alkaline Phosphates in Osteoblastic Osteosarcoma Cells,” J. Biol. Chem. 1982 257:3362-3365. (Exhibit 96).Applicant
• Periasamy, Muthu et al., “Regulation of myosin heavy-chain gene expression during sleletal-muscle hypertrophy,” Biochem. J. 1989 257:691-698. (Exhibit 97).Applicant
• Poliard, A. et al., “Controlled Conversion of an Immortalized Mesodermal progenitor Cell Towards osteogenic, Chondrogenic, or Adipogenic Pathways,” J. Cell Biol. 1995 130;1461-1472. (Exhibit 98).Applicant
• Price, Paul A. et al., “Matrix GLA Protein, A New γ-Carboxyglutamic Acid-Containing Protein Which is Associated With the Organic Matrix of Bone,” Biochem. Biophys. Res. Commun., 1983 117:765-771. (Exhibit 99).Applicant
• Rando, Thomas A. and Helen M. Blau, “Primary Mouse Myoblast Purification, Characterization, and Transplantation for Cell-mediated Gene Therapy,” J. Cell Biol 1994 125:1275-1287. (Exhibit 100).Applicant
• Weiner, Francis R. et al., “Regualtion of collagen Gene Expression in 3T3-L1 Cells. Efects of Adipocyte Differentiation and Tumor necrosis Factor α,” Biochem 1989 28:4094-4099. (Exhibit 101).Applicant
• Williams, Irene H. and S. Efthimios Polakis, “Differentiation of 3T3-L1 Fibroblasts to Adipocytes the Effect of Indomethacin, Prostaglandin E1 and Cyclic AMP on The Process of Differentiation,” Biochem. Biophys. Res. Commun. 1977 77:175-186. (Exhibit 102).Applicant
• Wise, Leigh S. and Howard Green, “Participation of One Isozyme of Cytosolic Glycerophosphate Dehydrogenase in the Adipose Conversion of 3T3 Cells,” J. Biol. Chem. 1979 254:273-275. (Exhibit 103).Applicant
• Yoon, Kyonggeun et al., “Characterization of the Rat osteocalcin Gene: Stimulation of Promoter Activity by 1,25-Dihydroxyvitamin D3,” Biochem. 1988 27:8521-8526. (Exhibit 104).Applicant
• Bastard, J. P. et al., “A Mini-Liposuction Technique Adapted to the Study of Human Adipocyte Glucose Transport System,” Diabetologia, 36(Suppl. 1)A135, 1993 (Exhibit 120).Applicant
• Caplan, Arnold I., “The Mesengenic Process,” Clinics in Plastic Surgery, 21:429-35. 1994 (Exhibit 121).Applicant
• Crandall, David L. et al., “Identification of Estrogen Receptor β RNA in Human Breast and Abdominal Subcutaneous Adipose Tissue” Biochemical and Biophysical Research Communications, 248:523-6, 1998 (Exhibit 122).Applicant
• Hauner, Hans et al., “Promoting Effect of Glucocorticoids on the Differentiation of Human Adipocyte Precursor Cells Cultured in a Chemically Defined Medium,” Journal of Clinical Investigation, 84:1663-70, 1989 (Exhibit 123).Applicant
• Hauner H. et al., “Glucocorticoids and Insulin Promote the Differentiation of Human Adipocyte Precursor Cells into Fat Cells,” Journal of Clinical Endocrinology and Metabolism, 64:832-5, 1987 (Exhibit 124).Applicant
• Johnson, P. R. et al., “Uncontrolled adipocyte proliferation is not the primary lesion in the genetically-obese Zucker rat,” International Journal of Obesity, 5:563-70, 1981 (Exhibit 125).Applicant
• Killinger, D. W. et al., “Influence of Adipose Tissue Distribution on the Biological Activity of Androgens,” Annals New York Academy of Sciences, 595:199-211. 1990 (Exhibit 126).Applicant
• Killinger, Donald W. et al., “The Relationship Between Aromatase Activity and Body Fat Distribution,” Steroids, 50:61-72. 1987 (Exhibit 127).Applicant
• Lafontan, M. et al., “Réflexions sur une nouvelle approche de chirurgie plastique réparatrice: la réimplantation de fragments de tissu adipeux prélevés par liposuccion,” Ann. Chur. Plast. Esthet., 34:77-81, 1989 (Exhibit 128).Applicant
• Lam, Anson and Ronald Moy, “The Potential for Fat Transplantation,” J. Dermatol. Surg. Oncol., 18:432-4, 1992 (Exhibit 129).Applicant
• Lecoeur, L. and J. P. Ouhayoun, “In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells.” Biomaterials, 18:989-93, 1997 (Exhibit 130).Applicant
• Loncar, D., “Ultrastructural analysis of differentiation of rat endoderm in vitro. Adipose vascular-strōmal cells induce endoderm differentiation, which in turn induces differentiation of the vascular-stromal cells into chondrocytes,” J. Submicrosc. Cytol. Pathol., 24:509-19. 1992 (Exhibit 131).Applicant
• Novakofski, Jan E., “Primary Cell Culture of Adipose Tissue,” Biology of the Adipocyte: Research Approaches, Van Nostrand Reinhold Company, NY, 1987 160-97 (Exhibit 132).Applicant
• Pedersen, S. B. et al., “Identification of oestrogen receptors and oestrogen receptor mRNA in human adipose tissue,” European Journal of Clinical Investigation, 26:262-9, 1996 (Exhibit 133).Applicant
• Pettersson, Per et al., “Adipocyte Precursor Cells in Obese and Nonobese Humans,” Metabolism, 34:808-12. 1985 (Exhibit 134).Applicant
• Ramsay, T. G. et al., “Pre-Adipocyte Proliferation and Differentiation in Response to Hormone Supplementation of Decapitated Fetal Pig Sera,” J. Anim. Sci., 64:735-44, 1987 (Exhibit 135).Applicant
• Rubens, F. D. et al., “Tissue Factor Expression by Cells Used for Sodding of Prosthetic Vascular Grafts.” Journal of Surgical Research, 72:22-8, 1997 (Exhibit 136).Applicant
• Smahel, J., “Aspiration lipectomy and adipose tissue injection: pathophysiologic commentary,” European Journal of Plastic Surgery, 14:126-31, 1991 (Exhibit 137).Applicant
• Springhorn, Jeremy P. et al., “Human Capillary Endothelial Cells from Abdominal Wall Adipose Tissue: Isolation Using an Anti-Pecam Antibody,” In Vitro Cellular & Developmental Biology-Animal, 31:473-81, 1995 (Exhibit 138).Applicant
• Tavassoli, Mehdi, “In Vivo Development of Adipose Tissue Following Implantation of Lipid-Depleted Cultured Adipocyte,” Experimental Cell Research, 137:55-62, 1982 (Exhibit 139).Applicant
• Williams, John T. et al., “Cells Isolated from Adult Human Skeletal Muscle Capable of Differentiating into Multiple Mesodermal Phenotypes,” The American Surgeon, 65:22-6. 1999 (Exhibit 140).Applicant
• Williams, Stuart K. et al., “Liposuction-derived human fat used for vascular graft sodding contains endothelial cells and not mesothelial cells as the major cell type,” Journal of Vascular Surgery, 19:916-23, 1994 (Exhibit 141).Applicant
• Wlodarski, Krzysztof H., “Section III. Basic Science and Pathology. Properties and Origin of Osteoblasts,” Clinical Orthopaedics and Related Research, 252:276-93, 1990 (Exhibit 142).Applicant
• Ahrens, Patricia Buckley et al., “Stage-Related Capacity for Limb Chondrogenesis in Cell Culture,” Developmental Biology, 1977, 60:69-82 (Exhibit 143).Applicant
• Alameddine, Hata S. et al., “Regeneration of Skeletal Muscle Fibers from Autologous Satellite Cells Multiplied In Vitro. An Experimental Model for Testing Cultured Cell Myogenicity,” Muscle & Nerve, 1989, 12:544-55 (Exhibit 144).Applicant
• Angele. P. et al., “Engineering of Osteochondral Tissue with Bone Marrow Mesenchymal Progenitor Cells in a Derivatized Hyaluronan-Gelatin Composite Sponge,” Tissue Engineering, 1999, 5:545-53 (Exhibit 145).Applicant
• Bailey, A. J. et al., “Age-Related Changes in the Biochemical Properties of Human Cancellous Bone Collagen: Relationship to Bone Strength,” Calcified Tissue International, 1999, 65:203-10 (Exhibit 146).Applicant
• Barghom, A. et al., “α-Smooth Muscle Actin Distribution in the Pulmonary Vasculature Comparing Hypoplastic and Normal Fetal Lungs,” Pediatric Pathology & Laboratory Medicine, 1998, 18:5-22 (Exhibit 147).Applicant
• Baylink, David J., “Glucocorticoid-Induced Osteoporosis,” The New England Journal of Medicine, 1983, 309:306-8 (Exhibit 148).Applicant
• Becerra, José et al., “Demineralized Bone Matrix Mediates Differentiation of Bone Marrow Stromal Cells In Vitro: Effect of Age of Cell Donor,” Journal of Bone and Mineral Research, 1996, 11:1703-14 (Exhibit 149).Applicant
• Beiser, Ian H. and Irvin O. Kanat, “Subchondral Bone Drilling: A Treatment for Cartilage Defects,” Journal of Foot Surgery, 1990, 29:595-601 (Exhibit 150).Applicant
• Breen, Ellen C. et al., “TGFβ Alters Growth and Differentiation Related Gene Expression in Proliferating Osteoblasts In Vitro, Preventing Development of the Mature Bone Phenotype”, Journal of Cellular Physiology, 1994, 160:323-35 (Exhibit 151).Applicant
• Bruder, Scott P. et al., “Bone Regeneration by Implantation of Purified, Culture-Expanded Human Mesenchymal Stem Cells,” Journal of Orthopaedic Research, 1998, 16:155-62 (Exhibit 152).Applicant
• Butnariu-Ephrat, Miriam et al., “Resurfacing of Goat Articular Cartilage by Chondrocytes Derived From Bone Marrow,” Clinical Orthopaedics and Related Research, 1996, 330:234-43 (Exhibit 153).Applicant
• Campion, Dennis R., “The Muscle Satellite Cell: A Review,” Internationals Review of Cytology, 1984, 87:225-51 (Exhibit 154).Applicant
• Caplan, Arnold I., “Mesenchymal Stem Cells,” Journal of Orthopaedic Research, 1991, 9:641-50 (Exhibit 155).Applicant
• Caplan, Arnold I., “The Mesengenic Process,” Clinics in Plastic Surgery, 1994, 21:429-35 (Exhibit 156).Applicant
• Carranza-Bencano, A. et al., “Comparative Study of the Reconstruction of Articular Cartilage Defects with Free Costal Perichondrial Grafts and Free Tibial Periosteal Grafts: An Experimental Study on Rabbits,” Calcified Tissue International, 1999, 65:402-7 (Exhibit 157).Applicant
• Chen, Xiaoli et al., “Differentiation-dependent expression of obese (ob) gene by preadipocytes and adipocytes in primary cultures of porcine stromal-vascular cells,” Biochimica et Biophysica Acta, 1997, 1359:136-42 (Exhibit 158).Applicant
• Chimal-Monroy, Jesús and Lino Diaz de León, “Expression of N-cadherin, N-CAM, fibronectin tenascin is stimulated by TGF-β1, β2, β3 and β5 during the formation of precartilage condensations,” The International Journal of Developmental Biology, 1999, 43:59-67 (Exhibit 159).Applicant
• Deng, Weiwen et al., “In Vitro Differentiation of Human Marrow Stromal Cells into Early Progenitors of Neural Cells by Conditions That Increase Intracellular Cyclic AMP,” Biochemical and Biophysical Research Communications, 2001, 282:148-52 (Exhibit 160).Applicant
• Dennis, James E. et al., “A Ouadripotential Mesenchymal Progenitor Cell Isolated from the Marrow of an Adult Mouse,” Journal of Bone and Mineral Research, 1999, 14:700-9 (Exhibit 161).Applicant
• Dias, Peter et al., “The Molecular Basis of Skeletal Muscle Differentiation,” Seminars in Diagnostic Pathology, 1994. 11:3-14 (Exhibit 162).Applicant
• Diefenderfer, David L. and Carl T. Brighton, “Microvascular Pericytes Express Aggrecan Message Which is Regulated by BMP-2,” Biochemical and Biophysical Research Communications, 2000, 269:172-8 (Exhibit 163).Applicant
• Eisenberg, Shlomo, “High density lipoprotein metabolism,” Journal of Lipid Research, 1984, 25:1017-58 (Exhibit 164).Applicant
• Fajas, Lluis, et al., “Transcriptional control of adipogenesis,” Current Opinion in Cell Biology, 1998, 10:165-73 (Exhibit 165).Applicant
• Farndale, Richard W. et al., “Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylene blue,” Biochimica et Biophysica Acta, 1986. 883:173-7 (Exhibit 166).Applicant
• Fülöp, Csaba et al., “Expression of Alternatively Spliced Epidermal Growth Factor-like Domains in Aggrecans of Different Species,” The Journal of Biological Chemistry, 1993, 268:17377-83 (Exhibit 167).Applicant
• Glowacki, J., “Influence of Age on Human Marrow,” Calcified Tissue International, 1995, 56(Supp. 1):S50-1 (Exhibit 168).Applicant
• Grigoriadis, Agamemnon E. et al., “Analysis of chondroprogenitor frequency and cartilage differentiation in a novel family of clonal chondrogenic rat cell lines,” Differentiation, 1996, 60:299-307 (Exhibit 169).Applicant
• Hardingham, Tim et al., “Studies on the Synthesis, Secretion and Assembly of Proteoglycan Aggregates by Chondrocytes,” Matrices and Cell Differentiation, 1984, 151:17-29 (Exhibit 170).Applicant
• Haynesworth, S. E. et al., “Cell Surface Antigen on Human Marrow-Derived Mesenchymal Cells are Detected by Monoclonal Antibodies,” Bone, 1992, 13:69-80 (Exhibit 171).Applicant
• Huss, Ralf, “Isolation of Primary and Immortalized CD34 Hematopoietic and Mesenchymal Stem Cells from Various Sources,” Stem Cells, 2000. 18:1-9 (Exhibit 172).Applicant
• Iwasaki, Motoki et al., “Regulation of Proliferation and Osteochondrogenic Differentiation of Periosteum-Derived Cells by Transforming Growth Factor-β and Basic Fibroblast Growth Factor,” Journal of Bone and Joint Surgery, 1995, 77A:543-54 (Exhibit 173).Applicant
• Katz, Adam J. et al., “Emerging Approaches to the Tissue Engineering of Fat,” Clinics in Plastic Surgery, 1999, 26:587-603 (Exhibit 174).Applicant
• Kirsch, Thorsten and Klaus von der Mark, “Remodelling of collagen types I, II and X and calcification of human fetal cartilage,” Bone and Mineral, 1992, 18:107-17 (Exhibit 175).Applicant
• Kosher, Robert A. and Michael Solursh, “Widespread Distribution of Type II Collagen during Embryonic Chick Development,” Developmental Biology, 1989, 131:558-66 (Exhibit 176).Applicant
• Lazarus, Hillard M. et al., “Human Bone Marrow-Derived Mesenchymal (Stromal) Progenitor Cells (MPCs) Cannot Be Recovered from Peripheral Blood Progenitor Cell Collections,” Journal of Hematotherapy, 1997, 6:447-55 (Exhibit 177).Applicant
• Leboy, Phoebe S. et al., “Ascorbic Acid Induces Alkaline Phosphatase, Type X Collagen, and Calcium Deposition in Cultured Chick Chondrocytes,” The Journal of Biological Chemistry, 1989, 264:17281-6 (Exhibit 178).Applicant
• Lee, Yun-Shain and Cheng-Ming Chuong, “Adhesion Molecules in Skeletogenesis: I. Transient Expression of Neural Cell Adhesion Molecules (NCAM) in Osteoblasts During Endochondral and Intramembranous Ossification,” Journal of Bone and Mineral Research, 1992, 7:1435-46 (Exhibit 179).Applicant
• Lennon, Donald P. et al., “Human and Animal Mesenchymal Progenitor Cells from Bone Marrow: Identification of Serum for Optimal Selection and Proliferation” In Vitro Cell. Dev. Biol.—Animal, 1996, 32:602-11 (Exhibit 160).Applicant
• Lev, Robert and S. S. Spicer, “Specific Staining of Sulphate Groups with Alcian Blue at Low pH,” J. Histochem. Cytochem., 1964. 12:309-10 (Exhibit 181).Applicant
• Long, Michael W. et al., “Age-Related Phenotypic Alterations in Populations of Purified Human Bone Precursor Cells,” The Journals of Gerontology, 1999, 54A:854-62 (Exhibit 182).Applicant
• Lucas, P. A. et al., “Isolation of Putative Mesenchymal Stem Cells from Rat Embryonic and Adult Skeletal Muscle,” In Vitro Cell Dev. Biol., 1992, 28:154A (Exhibit 183).Applicant
• MacDougald, Ormond A. and M. Daniel Lane, “Transcriptional Regulation of Gene Expression During Adipocyte Differentiation,” Annu. Rev. Biochem., 1995, 64:345-73 (Exhibit 184).Applicant
• Mullen, Richard J. et al., “NeuN, a neuronal specific nuclear protein in vertebrates,” Development, 1992. 116:201-11 (Exhibit 185).Applicant
• Nagle, R. B. et al., “Factor VII-Associated Antigen in Human Lymphatic Endothelium,” Lymphology, 1987, 20:20-4 (Exhibit 186).Applicant
• Nakahara, H. et al., “Bone and Cartilage Formation in Diffusion Chambers by Subcultured Cells Derived from the Periosteum” Bone, 1990, 11:181-8 (Exhibit 187).Applicant
• Nakano, Hirotaka et al., “RT-PCR Suggests Human Skeletal Muscle Origin of Alveolar Soft-Part Sarcoma” Oncology, 2000, 58:319-23 (Exhibit 188).Applicant
• O'Driscoll, Shawn W., “Current Concepts Review: The Healing and Regeneration of Articular Cartilage,” Journal of Bone and Joint Surgery, 1998. 80A:1795-812 (Exhibit 189).Applicant
• Olson, E. N. et al., “Know Your Neighbors: Three Phenotypes in Null Mutants of the Myogenic bHLH Gene MRF4,” Cell, 1996. 85:1-4 (Exhibit 190).Applicant
• Pairault, Jacques and Howard Green, “A study of the adipose conversion of suspended 3T3 cells by using glycerophosphate dehydrogenase as differentiation marker,” Proc. Natl. Acad. Sci. USA, 1979, 76:5138-42 (Exhibit 191).Applicant
• Park, S. R. et al., “Interconversion Potential of Clone Human Marrow Adipocytes In Vitro,” Bone, 1999, 24:549-54 (Exhibit 192).Applicant
• Pettersson, Per et al., “Cells in Human Adipose Tissue Developing into Adipocytes,” Acta Med Scand, 1984, 215:447-51 (Exhibit 193).Applicant
• Pierelli, Luca et al., “CD34+/CD105+ cells are enriched in primitive circulating progenitors residing in the G0 phase of the cell cycle and contain all bone marrow and cord blood CD34+/CD38tcmd- precursors,” British Journal of Haematology, 2000, 108:610-20 (Exhibit 194).Applicant
• Price, Paul A., “GLA-Containing Proteins of Bone,” Connective Tissue Research, 1989, 21:51-60 (Exhibit 195).Applicant
• Price, Paul A. and Sharon A. Baukol, “1,25-Dihydroxyvitamin D3 Increases Synthesis of the Vitamin K-dependent Bone Protein by Osteosarcoma Cells, ” The Journal of Biological Chemistry, 1980, 255:11660-3 (Exhibit 196).Applicant
• Probst, M. et al., “Homologous bladder augmentation in dog with the bladder acellular matrix graft,” BJU International, 2000.85:362-71 (Exhibit 197).Applicant
• Richardson, J. B. et al., “Repair of human articular cartilage after implantation of autologous chondrocytes,” The Journal of Bone and Joint Surgery, 1999.81:1064-8 (Exhibit 198).Applicant
• Rickard, David J. et al., “Isolation and Characterization of Osteoblast Precursor Cells from Human Bone Marrow,” Journal of Bone and Mineral Research, 1996, 11:312-24 (Exhibit 199).Applicant
• Sarnat, Harvey B. et al., “Neuronal nuclear antigen (NeuN): a marker of neuronal maturation in the early human fetal nervous system,” Brain & Development, 1998, 20:88-94 (Exhibit 200).Applicant
• Scott, Douglas M. et al., “Collagen Synthesis in Cultured Osteoblast-like Cells,” Archives of Biochemistry and Biophysics, 1980, 201:384-91 (Exhibit 201).Applicant
• Shalhoub, Victoria et al., “Downregulation of Cell Growth and Cell Cycle Regulated Genes during Chick Osteoblast Differentiation with the Reciprocal Expression of Histone Gene Variants,” Biochemistry, 1989, 28:5318-22 (Exhibit 202).Applicant
• Siffert, Robert S., “The Role of Alkaline Phosphatase in Osteogenesis,” The Journal of Experimental Medicine, 1951, 93:415-26 (Exhibit 203).Applicant
• Syrjälä, M. et al., “A flow cytometric assay of CD34-postitive cell populations in the bone marrow,” British Journal of Haematology, 1994, 88:679-84 (Exhibit 204).Applicant
• Tacchetti, C. et al., “In Vitro Morphogenesis of Chick Embryo Hypertrophic Cartilage,” The Journal of Cell Biology, 1987, 105:999-1006 (Exhibit 205).Applicant
• Tontonoz, Peter et al., “mPPARγ2: tissue-specific regulator of an adipocyte enhancer,” Genes & Development, 1994, 8:1224-34 (Exhibit 206).Applicant
• Trayhum, P. and Margaret Ashwell. “Control of white and brown adipose tissues by the autonomic nervous system,” The Proceedings of the Nutrition Society, 1987, 46:135-42 (Exhibit 207).Applicant
• Vandenburgh, Herman H. and Patricia Karlisch, “Longitudinal Growth of Skeletal Myotubes In Vitro in a New Horizontal Mechanical Cell Stimulator,” in Vitro Cellular & Developmental Biology, 1989, 25:607-16 (Exhibit 208).Applicant
• Wakitani, Shigeyuki et al., “Mesenchymal Cell-Based Repair of Large, Full-Thickness Defects of Articular Cartilage,” The Journal of Bone and Joint Surgery, 1994, 76A:579-92 (Exhibit 209).Applicant
• Wakitani, Shigeyuki et al., “Myogenic Cells Derived from Rat Bone Marrow Mesenchymal Stem Cells Exposed to 5-Azacytidine,” Muscle & Nerve, 1995, 18:1417-26 (Exhibit 210).Applicant
• Weintraub, Harold et al. “Tissue-specific gene activation by MyoD: determination of specificity by cis-acting repression elements,” Genes & Development, 1994, 8:2203-11 (Exhibit 211).Applicant
• Yoo, Jung U. and Brian Johnstone, “The Role of Osteochondral Progenitor Cells in Fracture Repair,” Clinical Orthopaedics and Related Research, 1998, 355S:S73-81 (Exhibit 212).Applicant
• Young, Henry E. et al., “Human Pluripotent and Progenitor Cells Display Cell Surface Cluster Differentiation Markers CD10, CD13, CD56, and MHC Class-I (44385),” Proc. Soc. Exp. Biol. Med., 1999, 221:63-71 (Exhibit 213).Applicant
• Zezulak, Kathleen M. and Howard Green, “Specificity of Gene Expression in Adipocytes,” Molecular and Cellular Biology, 1985, 5:419-21 (Exhibit 214).Applicant
• Zohar, R. et al, “Analysis of intracellular osteopontin as a marker of osteoblastic cell differentiation and mesenchymal cell migration,” European Journal of Oral Sciences, 1998, 106(Supp. 1):401-7 (Exhibit 215).Applicant
• Zuk, Patricia Z. et al., “Multilineage Cells from Human Adipose Tissue: Implication for Cell-Based Therapies,” Tissue Engineering, 2001, 7:211-28 (Exhibit 216).Applicant
• Boskey, et al., 1985, “The Effect of Osteocalcin on In Vitro Lipid-Induced Hydroxyapatite Formation and Seeded Hydroxyapatite Growth,” Calc. Tiss. Int. 37:75. (Exhibit 217).Applicant
• Fortier, Lisa, et al., 2000, “Isolation and chondrocytic differentiation of equine bone marrow-derived mesenchymal stem cells,” Am. J. Vet. Res. 59:1182-1187. (Exhibit 218).Applicant
• Huibregtse, Barbara, et al., 1998, “Effect of Age and Sampling Site on the Chondro-Osteogenic Potential of Rabbit Marrow-derived Mesenchymal Progenitor Cells,” Journal of Orthopaedic Research18:18-24, (Exhibit 219).Applicant
• Linsenmayer, Thomas et al., 1998, “Type X Collagen: A Hypertrophic Cartilage-Specific Molecule,” Pathol. lmmunopathol. 7:14-19. (Exhibit 220).Applicant
• Nakajima, I. et al., 1998, “Adipose tissue extracellar matrix: newly organized by adipocytes during differentiation,” Differentiation 63:193-200, (Exhibit 221).Applicant
• Zvaifler, et al., 2000, “Mesenchymal precursor cells in the blood of normal individuals,” Arthritis Res. 2:477-488, (Exhibit 222).Applicant
• Bond et al., 1999, “Human Subcutaneouspreadipocytes Differentiate Into osteoblasts,” FASEB Journal 13:600A (Exhibit 225).Applicant
• Smith et al., 2000, “Mesenchymal Stem Cells Derived From Bone Marrow and Human Adipose Tissue Exhibit Multilineage Potential,” Journal of Investigative Medicine, 95A. (Exhibit 226).Applicant
• Stashower et al., 1999, “Stromal progenitor cells present within liposuction and reduction abdominoplasty fat for autologous transfer to aged skin,” Dermatologic Surgery, 25:12:945-949. (Exhibit 227).Applicant
• Strutt et al., 1996, “Growth and differentiation of human adipose stromal cells in culture,” methods in Molecular Medicine: Human Cell Culture Protools, 41-51. (Exhibit 228).Applicant
• Tavassoli et al., 1981, “The Nature of Fibroblasts Derived From Adipose Tissue In-Vitro,” Clinical Research, 29:5:871A. (Exhibit 229).Applicant
• Van et al., 1978, “Complete Differentiation of Adipocyte Precursors,” Cell Tissue, 195:317-329. (Exhibit 230).Applicant
• Soda, et al., 1983, “Adipocyte stem cell: A brief review,” Int. J. of Cell Cloning, 1:79-84, (Exhibit 234).Applicant
• Ailhaud, et al., 1983, “Hormonal requirements for growth and differentiation of OB17 preadipocyte cells in vitro,” Diabete & Metabolisme, vol. 9:125-133. (Exhibit 237).Applicant
• Ailhaud, et al., 1985, “Lipoprotiene lipase et differenciation adipocytaire,” Reprod. Nutr. Develop., vol. 25:153-158. (Exhibit 238).Applicant
• Zuk, Patricia A. et al., “Human Adipose Tissue is a Source of Multipotent Stem Cells,” Molecular Biology of the Cell, 2002, 13:4279-4295, (Exhibit 239).Applicant
• Gimble, Jeffery M. et al., “Adipose tissue-derived therapeutics,” Expert Opin. Biol., 2003, 3(5)705-713.. (Exhibit 240).Applicant
• Safford, Kristine M. et al., “Neurogenic differentiation of murine and human adipose-derived stromal cells,” Biochemical and Biophysical Research Communications, 2002, 371-379. (Exhibit 241).Applicant
• Abbate, A., Biondi-Zoccai, G.G. and Baldi, A. (2002) “Pathophysiologic role of myocardial apoptosis in post-infarction left ventricular remodeling” J Cell Physiol 193, 145-53.Applicant
• Aharinejad, S., Mars, S.C., Jr., Bock P., Mason-Savas, A., MacKay, C.A. Larson, E.K., Jackson, M.E., Luftensteiner, M. and Weisbauer, E. (1995) “CSF-1 treatment promotes angiogenesis in the metaphysics of osteopetrotic (toothless, tl) rats” Bone 16, 315-324.Applicant
• Aragona, F., L. D'Urso et al (1998) “Immunologic aspects of bovine injectable collagen in humans. A review” Eur Urol 33(2): 129-33.Applicant
• Arvidsson, A., Collin, T., Kirik, D., Kokaia, Z., and Lindvall, O. (2002) “Neuronal replacement from endogenous precursors in the adult brain after stroke” Nat Med 8, 963-70.Applicant
• Ashjian, P.H. Elbarbary, A.S., Edmonds, B., DeUgarte, D., Zhu, M., Zuk, P.A., Lorenz, H.P., Benhaim, P., and Hedrick, M.H. (2003). “In vitro differentiation of human processed lipoaspirate cells into early neural progenitors” Plast Reconstr Surg 111 1922-31.Applicant
• Asken, S. (1990) “Microliposuction and autologous fat transplantation for aesthetic enhancement of the aging face” J Dermatol Surg Oncol 16(10): 965-72.Applicant
• Asou, Y., Rittling, S.R., Yoshitake, H., Tsuji, K., Shinomiya, K., Nifuji, A., Denhardt, D.T., and Noda, M. (2001) “Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone” Endocrinology 142, 1325-1332.Applicant
• Assady, S., Maor, G., Amit, M., Itskovitz-Eldor, J., Skorecki, K.L., and Tzukerman, M. (2001) “Insulin production by human embryonic stem cells” Diabetes 50, 1691-7.Applicant
• Assmus, B., Schachinger, V., Teupe, C., Britten,M., Lehmann, R., Dobert, N., Grunwald, F., Aicher, A., Urbich, C., Martin, H., Hoelzer, D., Dimeler, S., and Zeiher, A.M. (2002) Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI) Circulation 106, 3009-17.Applicant
• Athanasopoulos, T., Fabb, S., and Dickson, G. (2000) “Gene therapy vectors based on adeno-associated virus: characteristics and applications to acquired and inherited diseases (review)” Int J Mol Med 6, 363-75.Applicant
• ATTC Preservation Methods: Freezing and Free-Drying, ATCC, 2nd Edition, 1991.Applicant
• Bagnato, A. and Spinella, F. (2003) “Emerging role of endothelin-1 in tumor angiogenesis” Trends Endocrinol Metab 14, 44-50.Applicant
• Banfi, A., Bianchi, G., Galotto, M., Cancedda, R., and Quarto, R. (2001) “Bone marrow stromal damage after chemo/radiotherapy: occurrence, consequences and possibilities of treatment” Leuk Lymphoma 42, 863-70.Applicant
• Barker, J.N., Davies, S.M., DeFor, T., Ramsay, N. K., Weisdorf, D.J. and Wagner, J.E. (2001) “Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of huan leukocyte antigen-matched unrelated donor bone marrow: results of a matched-pair analysis” Blood 97, 2957-61.Applicant
• Barry, F.P., Boynton, R.E., Haynesworth, S., Murphy, J.M., and Zaia, J. (1999) “The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105)” Biochem Biophys Res Commun 265, 134-9.Applicant
• Beecken, W.D., Kramer, W., and Jonas, D. (2000) “New molecular mediators in tumor angiogenesis” J Cell Mol Med 4, 262-269.Applicant
• Berdel, W.E., Fink, U., Thiel, E., Stunkel, K., Greiner, E., Schwarzkopf, G., Reichert, A. and Rastetter, J. (1982) “Purification of human monocytes by adherence to polymeric fluorocarbon. Characterization of the monocyte-enriched cell fraction” Immunobiology 163, 511-520.Applicant
• Bergeon, M.T. (1967) “Collagen: a review” J Okla State Med Assoc 60(6): 330-2.Applicant
• Bickenbach, J.R. and Dunnwald, M. (2000) “Epidermal stem cells: characteristics and use in tissue engineering and gene therapy” Adv Dermatol 16, 159-83.Applicant
• Block, C.A., C.S. Cooper (2003) “Long-term Efficacy of periurethral collagen injection for the treatment of urinary incontinence secondary to myelomeningocele” J Urol 169(1): 327-329.Applicant
• Boener, C.F. (1988) “Allergic response to a porcine collagen corneal shield. Case report” Arch Opthalmol 106(2): 171.Applicant
• Boering, G. and A.J. Huffstadt (1967) “The use of derma-fat grafts in the face” Br J Plast Surg 20(2): 172-8.Applicant
• Bonner-Weir, S. and Sharma, A. (2002) “Pancreatic stem cells” J Pathol 197, 519-526.Applicant
• Botta, M., Manetti, F., and Corelli, F. (2000) “Fibroblast growth factors and their inhibitors” Curr. Pharm. Des 6, 1897-1924.Applicant
• Bulleid, J.J., D.C. John et al (2000) “Recombinant expression systems for the production of collagen” Biochem Soc Trans 28(4): 350-3.Applicant
• Burres, S. (2001) “Soft-tissue augmentation with fascian” Clin Plast Surg 28(1): 101-10.Applicant
• Buschmann, I.R. Busch, H.J., Mies, G., and Hossmann, K.A. (2003) “Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor” Circulation 108, 610-615.Applicant
• Caplan, A.I. and Bruder, S.P. (2001) “Mesenchymal stem cells: building blocks for molecular medicine in the 21st century” Trends Mol Med 7, 259-64.Applicant
• Carano, R.A. and Filvaroff, E.H. (2003) “Angiogenesis and bone repair” Drug Discov. Today 8, 980-989.Applicant
• Carmeliet, P. (2000) “Mechamisms of angiogenesis and arteriogenesis” Nat Med 6, 389-395.Applicant
• Chen, J. et al. Intravenous Administration of Human Bone Marrow Stromal Cells Induces Angiogenesis in the Ischemis Boundary Zone After Stroke in Rats, Circulation Research, Apr. 2003, vol. 92, pp. 692-699.Applicant
• Chen, J. et al. Intravenous Bone Marrow Stromal Cell Therapy Reduces Apoptosis and Promotes Endogenous Cell Proliferation After Stroke in Femal Rat, J. Neuroscience Research, Sep. 2003, vol. 73 pp. 778-786.Applicant
• Civin, C.I., Strauss, L.C., Fackler, M.J., Trischmann, T.M., Wiley, J.M., and Loken, M.R. (1990) “Positive stem cell selection-basic science” Prog Clin Biol Res 333, 387-401.Applicant
• Clarke, D. and Frisen, J. (2001) “Differentiation potential of adult stem cells” Curr Opin Genet Dev 11, 575-80.Applicant
• Commons, G.W., Halperin, B., and Chang, C.C. (2001) “Large-volume liposuction: a reviw of 631 consecutive cases over 12 years” Plast Reconstr Surg 108, 1753-63.Applicant
• Davis, P.F. and Z.M. Mackle (1981) “A simple procedure for the separation of insoluble collagen and elastin” Anal Biochem 115(1): 11-7.Applicant
• De Ugarte, D.A., Ashjian, P.H., Elbarbary, A., and Hedrick, M.H. (2003) “Future of fat as raw material for tissue regeneration” Ann Plast Surg 50, 215-9.Applicant
• D'Ippolito, G., Schiller, P.C., Ricordi, C., Roos, B.A., and Howard, G.A. (1999) “Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow” J Bone Miner Res 14, 1115-22.Applicant
• Donovan, D., Brown, N.J., Bishop, E.T. and Lewis, C.E. (2001) “Comparison of three in vitro human ‘angiogenesis’ assays with capillaries formed in vivo” Angiogenesis 4, 113-121.Applicant
• Engleholm, S.A., Spang-Thomsen, M., Brunner N., Nohr, I., and Vindelov, L.L. (1985) “Disaggregation of human solid tumors by combined mechanical and enzymatic methods” Br J Cancer 51, 93-8.Applicant
• Eppley, B.L., Smith, P.G., Sadove, A.M., and Delvino, J.J. (1990) “Experimental effects of graft revascularization and consistency on cervicofacial fat transplant survival” J Oral Maxillofac Surg 48, 54-62.Applicant
• Eschenhagen, T., Didie, M., Muzel, FI, Schubert, P., Schneiderbanger, K., and Zimmermann, W.H. (2002) “3D engineered hear tissue for replacement therapy” Basic Res Cardiol 97 Suppl 1, 1146-1152.Applicant
• Falla, N., Van V., Bierkens, J., Borremans, B., Schoeters, G., and Van Gorp, J. (1993) “Characterization of a 5-flurorouracil-enriched osteoprogenitor population of the murine bone marrow” Blood 82, 3580-91.Applicant
• Folkman, J. (1995) “Angiogenesis in cancer, vascular, rheumatoid and other disease” Nat Med 1, 27-31.Applicant
• Ford, C.N., P.A. Staskowski et al. (1995) “Autologous collagen vocal fold injection: a preliminary clinical study” Laryngoscope 105(9 Pt 1): 944-8.Applicant
• Formanek, M., Temmel, A., Knerer, B., Wilhelm, M., Millesi, W., and Kornfehl, J. (1998) “Magnetic cell separation for purification of human oral keratinocytes: an effective method for functional studies without prior cell subcultivation” Eur Arch Otorhinolaryngol 255, 211-215.Applicant
• Fulton et al., “Fat Grafting” Fundamentals of Cosmetic Surgery, Jul. 2001, vol. 19, No. 3.Applicant
• Garcia-Olmo et al., “Autologous Stem Cell Transplantation for Treatment of Rectovaginal Fistula in Perianal Crohn's Disease: A New Cell-Based Therapy”, Int. J Colorectal Dis (2003), 18:451-454.Applicant
• Gaustad, K.G., Boquest, A.C., Anderson, B.E., Gerdes, A.M., and Collas, P. (2004) “Differentiation of human adipose tissue stem cells using extracts of rat cardiomyocytes” Biochem. Biophys. Res Commun. 314, 420-427.Applicant
• Geiselhart, A., Neu, S., Buchholz, F., Lang, P., Niethammer, D., and Handgretinger, R. (1996) “Postive selection of CD56+ lymphocytes by magnetic cell sorting” Nat Immun. 15, 227-233.Applicant
• Greenberg, A.W. and Hammer, D.A. (2001) “Cell separation mediated by differential rolling adhesion” Biotechnol Bioeng 73 111-24.Applicant
• Groutz, A., J.G. Blavias et al (2000) “Outcome results of transurethral collagen injection for female stress incontinence: assessment by urinary incontinence score” J Urol 164(6): 2006-9.Applicant
• Haab, F., P.E. Zimmern et al (1997) Urinary stress incontinence due to intrinsic sphincteric deficiency: experience with fat and collagen periurethral injections: J Urol 157(4): 1283-6.Applicant
• Hagege, A.A., Carrion, C., Menasche, P., Vilquin, J.T., Duboc, D., Marolleau, J.P., Desnos, M., and Bruneval, P. (2003) “Viability and differentiation of autologous skeletal myoblast grafts in ischaemic cardiomyopathy” Lancet 361, 491-2.Applicant
• Hak et al., “Toxic effects of DMSO on cultured beating heart cells at temperatures above zero,” Cryobiology, 1973, 10:244-250.Applicant
• Hamel, M., T. Shaarawy et al (2001) “Deep sclerectomy with collagen implant in patients with glaucoma and high myopia” J Cataract Refract Surg 27(9): 1410-7.Applicant
• Hemstreet, G.P. 3, Enoch, P.G., and Pretlow, T.G. 2 (1980) “Tissue disaggregation of human renal cell carcinoma with further isopyknic and isokinetic gradient purification” Cancer Res 40, 1043-9.Applicant
• Hess, D.C. et al. Hematopoietic Origin of Microglial and Perivascular Cells in Brain, Experimental Neurology, Apr. 2004, vol. 186, pp. 134-144.Applicant
• Hsiung, M. W., P. Woo et al (2000) “Fat augmentation for glottic insufficiency” Laryngoscope 110(6): 1026-33.Applicant
• Jaiswal, R.K., Jaiswal, J., Bruder, S.P., Mbalaviele, G., Marshak, D.R., and Pittenger, M.F. (2000) “Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase” J Biol Chem 275, 9645-52.Applicant
• Jiang, Y., Jahagirdar, B.N., Reinhardt, R.L., Schwartz, R.E., Keene, C.D., Ortiz-Gonzalez, X.R., Reyes, M., Lenvik, T., Lund, T., Blackstad, M., Du, J., Aldrich, S., Lisberg, A., Low, W.C., Largaespada, D.A., and Verfaillie, C.M. (2002a) “Pluripotency of mesenchymal stem cells derived from adult marrow” Nature 418, 41-9.Applicant
• Jiang, Y., Vaessen, B., Lenvik, T., Blackstad, M., Reyes, M., and Verfaillie, C.M. (2002b) “Multipotent progentiro cells can be isolated from postnatal murine bone marrow, muscle, and brain” Exp Hematol 30, 896-904.Applicant
• Kamer, F.M. and M.M. Churukian (1984) “Clinical use of injectable collagen. A three-year retrospective review” Arch Otolaryngol 110(2): 93-8.Applicant
• Karlsson et al., “Long-term storage of tissues by cryopreservation: critical issues,” Biomaterials 1996, 17(3):243-256.Applicant
• Katz, B.E., Bruck, M.C. and Coleman, W. P. 3 (2001b) “The benefits of powered liposuction versus traditional liposuction: a paired comparison analysis” Dermatol Surg 27, 863-7.Applicant
• Kaushal, S., Amiel, G.E., Guleserian, K.J., Shapira, O.M., Perry, T., Sutherland, F.W., Rabkin, E., Moran, A.M. Schoen, F.J., Atala, A., Soker, S., Bischoff, J., and Mayer, J.E., Jr. (2001) “Functional small-diameter neovessels cretaed using endothelial progenitor cells expanded ex vivo” Nat Med 7, 1035-40.Applicant
• Kawamoto, A., Tkebuchava, T., Yamaguchi, J., Nishimura, H., Yoon, Y.S., Milliken, C., Uchida, S., Masuo, O., Iwaguro, H., Ma, H., Hanley, A., Silver, M., Kearney, M., Lorsordo, D.W., Isner, J.M. and Asara, T. (2003) “Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemia” Circulation 107, 461-8.Applicant
• Klein, A.W. (2001) “Skin filling. Collagen and other injectables of the skin” Dermatol Clin 19(3): 491-508, ix.Applicant
• Koufman, J.A. (1'991) “Lipoinjection for vocal cord paralysis” Laryngoscope 101(12 Pt 1): 1385.Applicant
• Lamouille, S., Mallet, C., Feige, J.J., and Bailly, S. (2002) “Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis” Blood 100, 4495-4501.Applicant
• Lasch, J., Kullertz, G., and Opalka, J.R. (2000) “Separation of erythrocytes into age-related fractions by density or size? Counterflow centrifugation” Clin Chem Lab Med 38, 629-632.Applicant
• Latoni, J.D., D.M. Marshall et al (2000 “Overgrowth of fat autotransplanted for correction of localized steroid-induced atrophy” Plast Reconstr Surg 106(7): 1566-9.Applicant
• Lehner, M. and Holter, W. (2002) “Endotoxin-free purification of monocytes for dendritic cell generation via discontinuous density gradient centrifugation based on diluted Ficoll-Paque Plus” Int Arch Allergy Immunol 128, 73-76.Applicant
• Lennon, D.P., Haynesworth, S.E., Young, R.G., Dennis, J.E., and Caplan, A.I. (1995) “A chemically defined medium supports in vitor proliferation and maintains the osteochondral potential of rat marrow-derived mesenchymal stem cells” Exp Cell Res 219, 211-22.Applicant
• Lin, et al. “Hematopoietic Stem Cells Contribute to the Regeneration of Renal Tubules After Renal Ischmia-Reperfusion Injury in Mice.” Journal of the American Society of Nephrology. 14: 1188-1199 (2003).Applicant
• Liu, S.H., R.S. Yang et al (1995) “Collagen in tendon, ligament and bone healing. A current review” Clin Orthop (318): 265-78.Applicant
• Luskey, B.D., Lim, B., Apperley, J.F., Orkin, S.H., and Williams, D.A. (199) “Gene transfer into murine hematopoietic stem cells and bone marrow stromal cells” Ann NY Acad Sci 612, 398-406.Applicant
• Luttun, A., Tjwa, M., Moons, L., Wu, Y., Angelillo-Scherrer, A., Liao, F., Nagy, J.A., Hooper, A., Priller, J., De Klerck, B., Compernolle, F., Daci, E., Bohlen, P., Dewerchin, M., Herbert, J.M., Fava, R., Matthys, P., Carmeliet, G., Collen, D., Dvorak, H.F., Hicklin, D.J., and Carmeliet, P. (2002) “Revascularization of ischemic tissues by PIGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Fltl” Nat Med 8, 831-40.Applicant
• Mainwaring, G. and Rowley, A.F. (1985) “Separation of leucocytes in the dogfish (Scyliorhinus canicula) using density gradient centrifugation and differential adhesion to glass coverslips” Cell Tissue Res 241, 283-90.Applicant
• Majumdar, M.K., Thiede, M.A., Mosca, J.D., Moorman, M., and Gerson, S.L. (1998) “Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells” J Cell Physiol 176, 57-66.Applicant
• Marchlinski, F.E., Falcone, R., lozzo, R.V., Reichek, N., Vassallo, J.A., and Eysmann, S.B. (1987) “Experimental myocardial cryoinjury: local electromechanical changes, arrhythmogenicity, and methods for determining depth of injury” Pacing Clin Electrophysiol 10, 886-901.Applicant
• Miller, J.J. and J.C. Poop (2002) “Fat hypertrophy after autologous fat transfer” Opthal Plast Reconstr Surg 18(3): 228-31.Applicant
• Mills, J.D., Fischer, D., and Villaneuva, F.S. (2000) “Coronary collateral development during chronic ischemia: serial assessment using harmonic myocardial contrast echocardiography” J Am Coll Cardiol 36 618-24.Applicant
• Miranville, et al. “Improvement of postnatal neovascularization by human adipose tissue-derived stem cells.” Circulation, American Heart Association. 110(3):349-355 (2004).Applicant
• Mohr, M., Dalmis, F., Hilgenfeld, E., Oelmann, E., Zuhisdorf, M., Kratz-Alberts, K., Nolte, A., Schmitmann, C., Onaldi-Mohr, D., Cassens, U., Serve, H., Sibrowski, W., Kienast, J., and Berdel, W.E. (2001) “Simultaneous immunomagnetic CD34+ cell selection and B-cell depletion in peripheral blood progenitor cell samples of patients suffering from B-cell non-Hodgkin's lymphoma” Clin Cancer Res 7, 51-57.Applicant
• Monteiro, P., Antunes, A., Goncalves, L.M., and Providencia, L.A. (2003) “Long-term clincal impact of coronary-collateral vessels after acute myocardial infarction” Rev. Port. Cardiol 22, 1051-1061.Applicant
• Morizono, K., De Ugarte, D.A., Zhu, M., Zuk, P., Elbarbary, A., Ashjian, P., Benhaim, P. Chen, I.S., and Hedrick, M.H. (2003) “Multilineage cells from adipose tissue as gene delivery vehicles” Hum Gene Ther 14, 59-66.Applicant
• Mosca, J.D. Hedricks, J.K. Buyaner, D., Davis-Sproul, J., Chuang, L.C., Majumdar, M.K., Chopra, R., Barry, F., Murphy, M., Thiede, M.A. Junker, U., Rigg, R.J., Forestell, S.P., Bohnlien, E., Storb, R., and Sandmaier, B.M. (2000) “Mesenchymal stem cells as vehicles for gene delivery” Clin Orthop 71-90.Applicant
• Mullins, R.J., C. Richards et al. (1996) “allergic reactions to oral, surgical and topical bovine collagen. Anaphylactic risk for surgeons” Aust N Z J Ophthalmol 24(3): 257-60.Applicant
• Myllyharju, J. (2000) “Recombinant collagen trimers from insect cells and yeast” Methods Mol Biol 139: 39-48.Applicant
• Nagy, J.A., Dvorak, A. M., and Dvorak, H.F. (2003) VEGF-A (164/165) and PIGF: roles in angiogenesis and arteriogenesis: Trends Cardiovasc Med 13, 169-175.Applicant
• Nathan, Suresh et al. “Cell-Based Therapy in the Repair of Osteochrondral Defects: A Novel Use for Adipose Tissue”, Tissue Engineering, vol. 9, No. 4, 2003.Applicant
• Nerem, R.M. and Ensely, A.E. (2004) “The tissue engineering of blood vessels and the heart” Am J Transplant 4 Supp 6, 36-42.Applicant
• Nguyen, A., K.A. Pasyk et al. (1990) “Comparative study of survival of autologous adipose tissue taken and transplanted by different techniques” Plast Reconstr Surg 85(3): 378-86; discussion 387-9.Applicant
• Odorico, J.S., Kaufman, D.S., and Thomson, J.A. (2001) “Multilineage differentiation from human embryonic stem cells lines” Stem Cells 19, 193-204.Applicant
• Ohgushi, H. and Caplan, A.I. (1999) “Stem cell technology and bioceramics: from cell to gene engineering” J Biomed Mater Res 48, 913-27.Applicant
• Ooi, K., M.P. Lacy et al (1991) “salt-soluble collagen and elastin in the human aorta and pulmonary artery” Exp Mol Pathol 55(1): 25-9.Applicant
• Pera, M.F., Reubinoff, B., and Trounson, A. (2000) “Human embryonic stem cells” J Cell Sci 113 (Pt 1) 5-10.Applicant
• Pipp, F., Heil, M., lssbrucker, K., Ziegelhoeffer, T., Martin, S., Van den, H.J., Weich, H., Fernandez, B., Golumb, G., Carmeliet, P., Schaper, W., and Clauss, M. (2003) “VEGFR-1-selective VEGF homologue PIGF is arteriogenic: evidence for a monocyte-mediated mechanism” Circ. Res 92, 378-385.Applicant
• Planat-Bernard, et al. “Plasticity of Human Adipose Lineage Cells toward Endothelial Cells Physiological and Therapeutic Perspectives.” Circulation, American Heart Association. 109(5):656-663 (2004).Applicant
• Prince, H.M., Bashford, J., Wall, D., Rischin, D., Parker, N., Toner, G.C., Seymour, J.F., Blakey, D., Haylock, D., Simmons, P., Francis, P., Wolf, M., Januszewicz, E.H., Richardson, G., Scarlett, J., and Briggs, P. (2002) “Isolex 300i CD34-selected cells to support multiple cycles of high-dose therapy” Cytotherapy 4, 137-45.Applicant
• Purna, S.K. and M. Babu (2000) “Collagen based dressings—a review” Burns 26(1): 54-62.Applicant
• Qian, X., Jin, L., and Lloyd, R.V. (1998) Percoll Density Gradient-Enriched Populations of Rat Pituitary Cells: Interleukin 6 Secretion, Proliferative Activity, and Nitric Oxide Synthase Expression: Endocr. Pathol. 9, 339-346.Applicant
• Quirici, N., Soligo, D., Bossolasco, P., Servida, F., Lumini, C., and Deliliers, G.L. (2002) “Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antiobidies” Exp Hematol 30, 783-91.Applicant
• Rangappa, S., Fen, C., Lee, E.H., Bongso, A., and Wei, E.S. (2003) “Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes” Ann Thorac. Surg 75, 775-779.Applicant
• Rehman, et al. “Angiogenic potential of subcutaneous adipose stromal cells for autologous cell therapy.” Journal of the American College of Cardiology. 41(6)(Suppl A): 308A (Mar. 19, 2003).Applicant
• Remacle, M., G. Lawson et al (1999) “Correcting vocal fold immobility by autologous collagen injection for voice rehabilitation. A short-term study.” Ann Otol Rhinol Laryngol 108(8): 788-83.Applicant
• Remme, W.J. (2000) “Overview of the relationship between ischemia and congestive heart failure” Clin Cardiol 23, 4-8.Applicant
• Reyes, M., Lund, T., Lenvik, T., Aguiar, D., Koodie, L., and Verfaillie, C.M. (2001) “Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells” Blood 98, 2615-2625.Applicant
• Russell, S.W., Doe, W.F., Hoskins, R.G. and Cochrane, C.G. (1976) “inflammatory cells in solid murine neoplasms. I. Tumor disaggregation and identification of constituent inflammatory cells” Int J Cancer 18, 322-30.Applicant
• Scherberich, A. and A. Beretz (2000) “Culture of vascular cells in tridimensional (3-D) collagen: a methodological review” Therapie 55(1): 35-41.Applicant
• Scholz, D., Cai, W.J., and Schaper, W. (2001) “Arteriogenesis, a new concept of vascular adaptation in occlusive disease” Angiogenesis 4, 247-257.Applicant
• Scholz, D., Elasaesser, H., Sauer, A., Friedrich, C., Luttun, A., Carmeliet, P., and Schaper, W. (2003) “Bone marrow transplantation abolishes inhibition of arteriogenesis in placenta growth factor (PIGF)—mice” J Mol Cell Cardiol 35, 177-184.Applicant
• Scholz,D., Ziegelhoeffer, T., Helisch, A., Wagner, S., Friedrich, C., Podzuweit, T. and Schaper, W. (2002) “Contribution of arteriogenesis and angiogenesis to postocculsive hindlimb perfusion in mice” J Mol Cell Cardiol 34, 775-787.Applicant
• Schwartz, R.E., Reyes, M., Koodie, L., Jiang, Y., Blackstad, M., Lund, T., Lenvik, T., Johnson, S., Hu, W.S. and Verfaillie, C.M. (2002) “Multipotent adult progentiro cells from bone marrow differentiate into functional hepatocyte-like cells” J Clin Invest 109, 1291-302.Applicant
• Schwartzmann, M. (2000) “Use of collagen membranes for guided bone regeneration: a review” Implant Dent 9(1): 63-6.Applicant
• Schweitzer, C.M., Van Der, Schoot, Ce, Drager, A.M., Van der Valk, P., Zevenbergen, A., Hooibrink, B., Westra, A.H., and Langenhuijsen, M.M. (1995) “Isolation and culture of human bone marrow endothelial cells” Exp Hematol 23, 41-8.Applicant
• Sclafani, A.P. and T. Romo, 3rd (2001) “Collagen, human collagen and fat: the search for a three-dimensional soft tissue filler” Facial Plast Surg 17(1): 79-85.Applicant
• Sclafani, A.P., T. Romo, 3rd et al. (2002) “Rejuvenation of the aging lip with an injectable acellular dermal graft (cymetra)” Arch Facial Plast Surg 4(4): 252-7.Applicant
• Sekiya, I., Larson, B.L., Smith, J.R., Pochampally, R., Cui, J.G., and Prockop, D.J. (2002) “Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality” Stem Cells 20, 530-541.Applicant
• Sergeant, P., Blackstone, E., and Meyns, B. (1997) “Early and late outcome after CABG in patients with evolving myocardial infarction” Eur J Cardiothorac. Surg 11, 848-856.Applicant
• Shigematsu, S., Yamauchi, K., Nakajima, K., Iijima, S., Aizawa, T., and Hashizume, K. (1999) “IGF-1 regulates migration and angiogenesis of human endothelial cells” Endocr. J 46 Suppl, S59-S62.Applicant
• Shore, J.W. (2000) “Injectable lyophilized particulate human fascia lata (Fascian) for lip, perioral and glabellar enhancement” Opthal Plast Reconstr Surg 16(1): 23-7.Applicant
• Silver, F.H. and G. Pins (1992) “Cell growth on collagen: a review of tissue engineering using scaffolds containing extracellular matrix” J Long Term Eff Med Implants 2(1): 67-80.Applicant
• Smith, J.W. (1997) “Apheresis techniques and cellular immunomodulation” Ther. Apher. 1, 203-206.Applicant
• Smith, R.J. and Sweetenham, J.W. (1995) “A mononuclear cell dose of 3 × 10(8)kg predicts early multilineage recovery in patients with malignant lymphoma treated with carmustine, etoposide, Ara-C and melphalan (BEAM) and peripheral blood progenitor cell transplantation” Exp Hematol 23, 1581-8.Applicant
• Smits, G., Holzgreve, W., and Hahn, S. (2000) “An examination of different Percoll density gradients and magnetic activated cell sorting (MACS) for the enrichment of fetal erythroblasts from maternal blood” Arch. Cynecol. Obstet. 263, 160-163.Applicant
• Sodian, R., Lemke, T., Fritsche, C., Hoerstrup, S.P, Fu, P., Potapov, E.V., Hausmann, H., and Hetzer, R. (2002) “Tissue-engineering bioreactors: a new combined cell-seeding and perfusion system for vascular tissue engineering” Tissue Eng 8, 863-870.Applicant
• Soli, M., Blanco, L., Riggert, J., Martinez, Clavel, A., Lucas, C., Lunghi, M., Belloni, M., Wolf, C., van Waeg, G., and Antoon; M. (2001) “A multicentre evaluation of a new filtration protocol for leucocyte depletion of high-haematocrit red blood cells collected by an utomated blood collection system” Vox Sang. 81, 108-112.Applicant
• Speranza, M.L. and G. Valentini (1986) “A simple procedure for the purification of neutral salt soluble type I collagen from skin” Rai J Biochem 35(1): 42-8.Applicant
• Stamm, C., Westphal, B., Kleine, H.D., Petzsch, M., Kittner, C., Klinge, H., Schumichen, C., Nienaber, C.A., Freund, M. and Steinhoffm G. (2003) “Autologous bone-marrow stem-cell transplantation for myocardial regeneration” Lancet 4, 45-46.Applicant
• Sundberg, C., Kowanetz, M., Brown, L.F., Detmar, M., and Dvorak, H.F. (2002) “Stable expression of antiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo” Lab invest 82, 387-401.Applicant
• Takasaki, et al (1995) “Human type VI collagen: purification from human subcutaneous fat tissue and an immunohistochemical study of morphea and systemic sclerosis” J Dermatol 22(7): 480-5.Applicant
• Toma, J.G., Akhavan, M., Fernandes, K.J., Barnabe-Heider, F., Sadikot, A., Kaplan, D.R. and Miller, F.D. (2001) “Isolation of multipotent adult stem cells from the dermis of mammalian skin” Nat Cell Biol 3, 778-84.2.Applicant
• Twentyman, P.R. and Yuhas, J.M. (1980) “Use of bacterial neutral protease for disaggregation of mouse tumours and multicellular tumor spheroids” Cancer Lett 9, 225-8.Applicant
• Uitto, J. (1971) “Collagen biosynthesis in human skin. A review with emphasis on scleroderma” Ann Clin Res 3(5): 250-8.Applicant
• Van Merris, V., Meyer, E., Dosogne, H., and Burvenich, C. (2001) “Separation of bovine bone marrow into maturation-related myeloid cell fractions” Vet. Immunol. Immunopathol. 83, 11-17.Applicant
• Walther, W. and Stein, U. (2000) Viral vectors for gene transfer: a review of their use in the treatment of human diseases: Drugs 609, 249-71.Applicant
• Wang, L., Zeng, H., Wang, P., Soker, S., and Mukhopadhyay, D. (2003) “Neuropilin-1 mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration” J Biol Chem 278, 48848-48860.Applicant
• Watts, M.J., Somervaille, T.C., Ings, S.J., Ahmed, F., Khwaja, A., Yong, K. and Linch, D.C. (2002) “Variable product purity and functional capacity after CD34 selection: a direct comparison of the CliniMACS (v2.1) and Isolex 300i(v2.5) clinical scale devices” Br J Haematol 118, 117-23.Applicant
• Williams, S.K., McKenney, S. and Jarrell, B.E. (1995) “Collagenase lot selection and purification for adipose tissue digestion” Cell Transplant 4, 281-9.Applicant
• Xiong, B., Gong, L.L., Zhang, F., Hu, M.B. and Yuan, H.Y. (2002) “TGF beta1 expression and angiogenesis in colorectal cancer tissue” World J Gastroenterol. 8, 496-498.Applicant
• Ye, Q., Zund, G., Benedikt, P., Jockenhoevel, S., Hoerstrup, S.P., Sakyama, S., Hubbell, J.A. and Turina, M. (2000) “Fibrin gel a three dimensional matrix in cardiovascular tissue engineering” Eur J Cardiothorac Surg 17, 587-91.Applicant
• Yokoyama, T., N. Yoshimural et al (2001) “Persistence and survival of autologous muscle derived cells versus bovine collagen as potential treatment of stress urinary incontinence” J Urol 165(1): 271-6.Applicant
• Young et al., “Mesenchymal Stem Cells Reside Within the Connective Tissues of Many Organs,” Developmental Dynamics 1995 202(2), 137-144.Applicant
• Young, H.E., Steele, T.A., Bray, R.A., Hudson, J., Floyd, J.A., Hawkins, K., Thomas K., Austin, T., Edwards, C. Cuzzourt, J., Duenzl, M., Lucas, P.A., and Black, A.C., Jr. (2001) “Human reserve pluripotent mesenchymal stem cells are present in the connective tissues of skeletal muscle and dermis derived from fetal, adult and geriatric donors” Anat Rec 264, 51-62.Applicant
• Zimmerman, W.H., Diddie, N., Wasmeier, G.H. Nixdorff, U., Hess, A., Meinychenko, I., Boy, O., Neuhuber, W.L., Weyand, M., and Eschenhagen, T. (2002) “Cardiac grafting of engineered heart tissue in syngenic rats” Circulation 106, 1151-1157.Applicant
• Zimmermann, W.H., Melnychenko, I., and Eschenhagen, T. (2004) “Engineered heart tisue for regeneration of diseased hearts” Biomaterials 25, 1639-1647.Applicant
• Supplemental European Search Report for European Patent Application No. EP 02805648 dated Sep. 5, 2006.Applicant
• International Search Report for International Patent Application No. PCT/US02/39465 dated Jun. 22, 2006.Applicant
• IPRP dated Jan. 18, 2007 containing Written Opinion dated Apr. 13, 2006 for International Patent Application No. PCT/US04/21483 dated Apr. 13, 2006.Applicant
• International Search Report for International Patent Application No. PCT/US2004/005117 dated Apr. 6, 2006.Applicant
• Supplemental Partial European Search Report for European Patent Application No. 2805565.5 dated Mar. 6, 2007.Applicant
• Supplemental European Search Report for European Patent Application No. 4777155.5 dated Aug. 4, 2006.Applicant
• Examination Report for European Patent Application No. 4756641.9 dated Jan. 19, 2007.Applicant
• Supplemental European Search Report for European Patent Application No. 4756641.9 dated Oct. 18, 2006.Applicant
• International Search Report for International Patent Application No. PCT/US2006/021017 dated Oct. 20, 2006.Applicant
• International Search Report for International Patent Application No. PCT/US2006/040221 dated Feb. 27, 2007.Applicant
• International Search Report for International Patent Application No. PCT/US2005/001267 dated Apr. 28, 2006.Applicant
• Supplemental Partial European Search Report for European Patent Application No. 04777586.1 dated Jun. 5, 2007.Applicant
• Supplemental European Search Report for European Patent Application No. 2805565.5 dated Jul. 4, 2007.Applicant
• International Search Report for International Patent Application No. PCT/US2005/046296 dated Jun. 26, 2007.Applicant
• Supplemental European Search Report for European Patent Application No. 4777586.1 dated Aug. 3, 2007.Applicant
• Supplemental European Search Report for European Patent Application No. 04713403.6 dated Jul. 11, 2007.Applicant
• Office Actions in U.S. Appl. No. 11/584,202, filed Oct. 20, 2006.Applicant
• Office Actions in U.S. Appl. No. 10/783,957, filed Feb. 20, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/884,861, filed Jul. 1, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/884,638, filed Jul. 2, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/877,822, filed Jun. 25, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/871,503, filed Jun. 18, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/885,293, filed Jul. 1, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/884,637, filed Jul. 1, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/884,639, filed Jul. 1, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/885,294, filed Jul. 1, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/884,871, filed Jul. 1, 2004.Applicant
• Office Actions in U.S. Appl. No. 10/614,431, filed Jul. 7, 2003.Applicant
• Office Actions in U.S. Appl. No. 10/614,392, filed Jul. 7, 2003.Applicant
• Office Actions in U.S. Appl. No. 10/614,644, filed Jul. 7, 2003.Applicant
• Office Actions in U.S. Appl. No. 10/614,648, filed Jul. 7, 2003.Applicant
• Office Actions in U.S. Appl. No. 10/614,643, filed Jul. 7, 2003.Applicant
• Office Actions in U.S. Appl. No. 10/242,094, filed Sep. 12, 2002.Applicant
• Office Actions in U.S. Appl. No. 10/325,728, filed Dec. 20, 2002.Applicant
• Office Actions in U.S. Appl. No. 11/317,422, filed Dec. 22, 2005.Applicant
• Office Actions in U.S. Appl. No. 11/138,083, filed May 25, 2005.Applicant
• Office Actions in U.S. Appl. No. 11/229,028, filed Sep. 15, 2005.Applicant
• Office Actions in U.S. Appl. No. 11/813,579, filed Jul. 9, 2007.Applicant
• Badiavas, et al. “Participation of bone marrow derived cells in cutaneous would healing.” Journal of Cellular Physiology. 196(2): 245-250 (2003).Applicant
• Kim, et al. “Wound healing effect of adipose-derived stem cells: A critical role of secretory factors on human dermal fibroblasts.” Journal of Dermatological Science. 48(1): 15-24 (2007).Applicant
• Supplementary European Search Report for International Application No. EP 04756623.7 dated Oct. 10, 2007.Applicant
• Alhadlaq et al. “Engineered adipose tissue from human mesenchymal stem cells maintains predefined shape and dimension: implications in soft tissue augmentation and reconstruction.” Tissue Eng 11, 556-566 (2005).Applicant
• Björntrop, et al. “Isolation and characterization of cells from rat adipose tissue developing into adipocytes.” J. Lipid Res. 19:316-324 (1978).Applicant
• Cho,S.W. et al. “Engineering of volume-stable adipose tissues.” Biomaterials 26, 3577-3585 (2005).Applicant
• Cho,S.W. et al. “Enhancement of adipose tissue formation by implantation of adipogenic-differentiated preadipocytes.” Biochem Biophys Res Commun 345, 588-594 (2006).Applicant
• Choi et al. “Adipose tissue engineering using mesenchymal stem cells attached to injectable PLGA spheres.” Biomaterials 26, 5855-5863 (2005).Applicant
• Choi,Y.S. et al. “Adipogenic differentiation of adipose tissue derived adult stem cells in nude mouse.” Biochem Biophys Res Commun 345, 631-637 (2006).Applicant
• Clavijo-Alvarez,J.A. et al. “A novel perfluoroelastomer seeded with adipose-derived stem cells for soft-tissue repair.” Plast Reconstr Surg 118, 1132-1142 (2006).Applicant
• Cronin,K.J. et al. “New murine model of spontaneous autologous tissue engineering, combining an arteriovenous pedicle with matrix materials.” Plast Reconstr Surg 113, 260-269 (2004).Applicant
• Ersek, Robert A. “Transplantation of Purified Autologous Fat: A 3-Year Follow-Up is Disappointing.” Plast. Reconst. Surg. 87(2):219-228 (1991).Applicant
• Fain et al. “Comparison of the Release of Adipolines by Adipose Tissue, Adipose Tissue Matrix, and Adipocytes from Visceral and Subcutaneous Abdominal Adipose Tissues of Obese Humans.” Endocrinology, 145(5):2273-2282 (2004).Applicant
• Ganey et al. “A potential role for cell-based therapeutics in the treatment of intervertebral disc herniation.” Eur Spine J, 11(Suppl.2):S206-214 (2002).Applicant
• Ganey, et al. “Intervertebral Disc Repair Using Adipose Tissue-Derived Stem and Regenerative Cells.” 34(21):2297-2304 (2009).Applicant
• Hemmrich,K. et al. “Implantation of preadipocyte-loaded hyaluronic acid-based scaffolds into nude mice to evaluate potential for soft tissue engineering.” Biomaterials 26, 7025-7037 (2005).Applicant
• Hironori et al. The Japan Endocrine Society Journal, 80(1):90 (Apr. 2004).Applicant
• Hong et al. “Adipose tissue engineering by human adipose-derived stromal cells.” Cells Tissues Organs 183, 133-140 (2006).Applicant
• Hur et al. Akt is a Key Modulator of Endothelial Progenitor Cell Trafficking in Ischemic Muscle. Stem Cells. 25:1769-1778 (2007).Applicant
• Jurgens et al. “Effect of tissue-harvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies.” Cell Tiss. Res. 332:415-426 (2008).Applicant
• Kimura et al. “Adipose tissue engineering based on human preadipocytes combined with gelatin microspheres containing basic fibroblast growth factor.” Biomaterials 24, 2513-2521 (2003).Applicant
• Lund et al. “Granulocyte colony-stimulating factor mobilized CFU-F can be found in the peripheral blood but have limited expansion potential.” Haematologica. 93(6):908-912 (2008).Applicant
• Masuda,et al. “Photocured, styrenated gelatin-based microspheres for de novo adipogenesis through corelease of basic fibroblast growth factor, insulin, and insulin-like growth factor I.” Tissue Eng 10, 523-535 (2004).Applicant
• Masuda et al. “Novel strategy for soft tissue augmentation based on transplantation of fragmented omentum and preadipocytes.” Tissue Eng 10, 1672-1683 (2004).Applicant
• Miranville et al. “Human adipose tissue-derived stem cells improve postnatal neovascularization.” International Journal of Obesity. 28(Suppl 1):S100 (May, 2004).Applicant
• Nambu et al. Japanese Society for Biomaterials, Conference Proceedings, 25:96 (2003).Applicant
• Patrick et al. “Long-term implantation of preadipocyte-seeded PLGA scaffolds.” Tissue Eng, 8(2):283-93 (2002).Applicant
• Patrick et al. “Preadipocyte Seeded PLGA Scaffolds for Adipose Tissue Engineering.” Tissue Eng. 5(2): 139-151 (1999).Applicant
• Piersma et al. “Migration of fibroblastoid stromal cells in murine blood.” Cell Tissue Kinet, 18:589-595 (1985).Applicant
• Stosich et al. “Adipose tissue engineering from human adult stem cells: clinical implications in plastic and reconstructive surgery.” Plast Reconstr Surg 119, 71-83 (2007).Applicant
• Tabata,Y. et al. “De novo formation of adipose tissue by controlled release of basic fibroblast growth factor.” Tissue Eng, 6:6279-289 (2000).Applicant
• Torio-Padron et al. “Engineering of adipose tissue by injection of human preadipocytes in fibrin.” Aesthetic Plast Surg 31, 285-293 (2007).Applicant
• von Heimburg, D. et al. “Human preadipocytes seeded on freeze-dried collagen scaffolds investigated in vitro and in vivo.” Biomaterials 22, 429-38 (2001).Applicant
• Walton et al. “De novo adipose formation in a vascularized engineered construct.” Microsurgery 24, 378-384 (2004).Applicant
• Wu et al. “Preparation and assessment of glutaraldehyde-crosslinked collagen-chitosan hydrogels for adipose tissue engineering.” J Biomed Mater Res A 81, 59-65 (2007).Applicant
• International Search Report, Jul. 30, 2003, PCT/US02/40921.Applicant
• International Search Report, Dec. 12, 2002, PCT/US02/29207.Applicant
• International Search Report, Apr. 6, 2005, PCT/US04/20594.Applicant
• International Search Report, Apr. 12, 2005, PCT/US04/21417.Applicant
• International Search Report, Apr. 12, 2005, PCT/US04/21549.Applicant
• International Search Report, Dec. 22, 2005, PCT/US04/21418.Applicant
• International Search Report, Dec. 30, 2005, PCT/US04/21415.Applicant
• International Search Report, Apr. 4, 2005, PCT/US04/21480.Applicant
• International Search Report, Apr. 12, 2005, PCT/US04/21391.Applicant
• Coleman III, et al. “Autologous Collagen? Lipocytic Dermal Augmentayion. A Histopathologic Study.” J. Dermatol. Surg. Oncol. vol. 19, 1032-1040 (1993).Applicant
• Katz et al. “A Novel Device for the Simple and Efficient Refinement of Liposuctioned Tissue.” Plastic and Reconstructive Surgery, vol. 107, No. 2, 595-597 (Feb. 2001).Applicant
• Carpandena, C.A. “Collagen alterations in adipose autograft's.” Aesthetic Plastic Surgery. vol. 18, 11-15 (1994).Applicant
• Sattler et al. “Liporecycling: a technique for facial rejuvenation and body contouring.” Dermantol. Surg. vol. 26, No. 12, 1140-1144 (Dec. 2000).Applicant
• Kale et al. “Bone marrow stem cells contribute to repair of the ischemically injured renal tubule.” J. Clinical Investigation, vol. 112, No. 1, 42-49 (Jul. 2003).Applicant
• Safford et al. “In vivo engraftment and differentiation of murine adipose derived stromal cells.” Blood, Vo. 100, No. 11, 731a, (Nov. 2002).Applicant
• Miranville et al. “Human adipose tissue-derived stem cells improve blood flow in the ischemic mouse hind-limb.” Circulation, vol. 108, No. 17, Supp. IV, 164 (Oct. 2003).Applicant
• Sivan-Loukianova et al. “CD34+ Blood cells accelerate vascularization and healing of diabetic mouse skin wounds.” J. Vascular Research, vol. 40, No. 4, 368-377 (Jul.-Aug. 2003).Applicant
• Supplementary European Search Report for European Patent Application No. EP 04756607 dated Nov. 14, 2007.Applicant
• Dengler T et al. 2002. Stem Cell Therapy for the Infarcted Heart (“Cellular Cardiomyoplasty”), Herz 27:598-610.Applicant
• Reinecke H et al. 2002. Skeletal muscle stem cells do not transdifferentiate into cardiomyocytes after cardiac grafting. J. Mol. Cell. Cardiol. 34: 241-249.Applicant
• Murry CE et al. 2004. Hematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 428: 664-668.Applicant
• European Search Report for European Patent Application No. EP 07124088 dated Apr. 25, 2008.Applicant
• International Search Report for International Patent Application No. PCT/US05/18605 dated Jul. 3, 2008.Applicant
• International Search Report for International Patent Application No. PCT/USO4/21419 dated Jul. 3, 2008.Applicant
• Jackson et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. Journal Clinical Investigation, 107(11): 1395-1402 (2001).Applicant
• Kamihata et al. “Improvement of collateral perfusion and regional function by implantation of peripheral blood mononuclear cells into ischemic hibernating myocardium.” Thromb Vascular Biology, 22:1804-1810 (2002).Applicant
• European Examination Report for European Application No. EP 05754073 dated Nov. 30, 2009.Applicant
• Martinez-Estrada et al. “Human adipose tissue as a source of Flk-1 <+> cells: new method of differentiation and expansion.” Cardiovascular Research. 65(2):328-333 (2005).Applicant
• Perin et al. “Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure,” Circulation. 107(18):2294-2302 (2003).Applicant
• Planat-Benard et al. “Spontaneous Cardiomyocyte Differentiation from Adipose Tissue Stroma Cells,” Circulation Research. 94(2):223-229 (2004).Applicant
• Rodriguez et al. “The human adipose tissue is a source of multipotent stem cells,” Biochimie. 87(1):125-128 (2005).Applicant
• Saito et al. “Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myorcardial infarction.” The Journal of Thoracic and Cardiovascular Surgery. 126(1) (2003).Applicant
• Schoeller et al. “Histomorphologic and volumetric analysis of implanted autologous preadipocyte cultures suspended in fibrin glue: a potential new source for tissue augmentation.” Aesthetic Plastic Surgery, 25(1):57-63 (2001).Applicant
• Supplementary European Search Report for European Application No. EP 04776784 dated Nov. 5, 2009.Applicant
• Supplementary European Search Report for European Application No. EP 05754073 dated Aug. 7, 2009.Applicant
• Urbich et al. “Endothelial Progenitor Cells,” Trends in Cardiovascular Medicine. 14(8):318-322 (2004).Applicant
• Wollert et al. “Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial.” The Lancet Limited. 364(9429):141-148 (2004).Applicant
• Request for Ex Parte Reexamination dated Oct. 14, 2009.Applicant
• Notice of Failure to Comply with Ex Parte Reexamination Request Filing Requirements dated Oct. 22, 2009.Applicant
• Response to Notice of Failure to Comply with Ex Parte Reexamination Request Filing Requirements dated Oct. 23, 2009.Applicant
• Response to Notice of Failure to Comply with Ex Parte Reexamination Request Filing Requirements dated Nov. 4, 2009.Applicant
• Notice of Reexamination Request Filing Date (Third Party Requester) dated Nov. 12, 2009.Applicant
• Notice of Assignment of Reexamination Request dated Nov. 12, 2009.Applicant
• Ex Parte Reexamination Communication dated Dec. 30, 2009.Applicant