Method of Treating Bacterial, Viral or Parasitic Diseases

This invention relates to a therapeutic action of reducing media for controlling bacterial and viral infection and parasitic infestion in human and animal host, by applying a therapeutic mixture consisting of Cysteine which is aminomercaptopropionic acid, and disodium thiosulfate. Said aminomercaptopropionic sodim salt in conjuction with reducing disodium thiosulfate perform after injection a permanent reducing action liberating charged hydrogen, and charged aminothiopropionic radical which are biologically active which is manifested by neutralizing, or transforming the bacteria and viruses to nonagressive macromolecules, while killing parasites.

The mechanism of action of cysteine the aminomercaptopropionic sodium salt in conjuction with disodium thiosulfate unfolds a reducing process in a reducing media, which consequently contributes to the development of nascent and biologically active charged hydrogen, as well as the development of nascent charged aminothiopropionic radical. The supposedly antibacterial and antiviral action is accomplished by the integration of charged hydrogen and charged aminothiopropionic radical from reduced aminomercaptopropionic sodium salt, which complete the bacterial and viral nucleoproteides and thus neutralize their activity, while charged aminothiopropionic radical which being unstable, when unite to diaminodithiodipropionic acid kills the parasites.

The regenerative reversible process in the formation of aminothiopropionic and aminomercaptopropionic acid to release the active charged hydrogen develops by inherent oxidizing process and the reducing action of disodium thiosulfate. The reverse process is manifested in permanently reducing charged aminothiopropionic acid to aminomercaptopropionic acid as long as it is of disposible hydrogen from thiosulfate reducing action developed by hydrolysis. Each oxidation and reduction is sustained in reversible conditions, which is very important timely and biologically.

Reversible oxidation and reduction of aminomercaptopropionic acid makes feasible that the combination of said compound with mild reducing agent such as disodium thiosulfate, partake in the formation of biologically active hydrogen, i.e., charged hydrogen and charged aminothiopropionic radical. Combining charged hydrogen and charged aminothiopropionic radical follows de-oxidation and neutralization of bacteria and viruses unsaturated macromolecules, while the parasites under such conditions are killed. Thus, the nascent charged hydrogen, and nascent charged aminothiopropionic radical by their reactivity promote the antibacterial and antiviral action, as well as the killing of parasites, which is the essence of this invention.

The charged hydrogen and the charged aminothiopropionic radical are capable to bind unsaturated compounds on which behavior is based antibacterial and antiviral action of this invention. For, macromolecules undoubtedly have no homogeneous charge distribution, which should provide potential sites for trapping displaced electrons or binding holes in addition to those sites associated with lattice imperfection.

The advantage of disclosed pharmacologically active reducing media with charged hydrogen radical, charged aminothiopropionic radical, resides in nontoxic quality of disclosed process. No side effects can be expected by application of simple aminomercaptopropionic sodium salt, added by disodium thiosulfate with reducing capabilities by evolving disposable charged hydrogen. The aminothiopropionic radical is of short duration, because emitting charged hydrogen. Therefore, no toxic action may be incurred anyhow. The aminomercaptopropionic acid is not toxic being a normal product of organism. The said aminothiopropionic acid being unstable in neutral and weakly alkaline media as is blood serum oxidizes to disulfide diacide by emitting hydrogen, is also a normal product of organism. The presence of disodium thiosulfate prevent the formation of disulfide. The disodium thiosulfate oxidizes to disodium sulfate by the way of hydrolysis emitting two charged hydrogen. Because the process of oxidation-reduction evolves in blood serum the presence of disodium thiosulfate diminishes the needed presence of aminomercaptopropionic acid or its sodium salt for several times as pharmacologically needed to produce and emit charged hydrogen for biologic synthesis, whereas the charged aminothiopropionic radical is permanently and succeedingly incorporated in nucleoproteides of bacteria and viruses and/or in killing parasites until complete exhaustion and consummation. Thus, no toxic action can be incurred, while disodium sulfate the only unassimilable product is eliminated from the organism.

Explaining the possible mechanism of action in controlling bacteria, viruses, and parasites it was observed that all purulent processes of chronic character, suppurations, pustules, furuncles, various abcesses, various eczemas, purulent staphlococcal infection, streptococcal infections, and other bacterial infections, mastites, actinomycosis, actinobacillosis, mycosis, mycetes, endometritis may be healed with therapeutical mixture of this invention. Furthermore, myxovirus infection, mixomatosis and the like infections are successfully controlled. Of the parasitic diseases, the protozoan diseases, parasites of the type ixodides. Teliasis, the parasitic sickness of eye conjunctives in bovine, mange in bovine and all animal are successfully exterminated with therapeutical mixture of this invention.

The application in humans is fulfilled with one injection at intervals of one or two days. The applications are fulfilled by priority intravenous, but may be applied intramuscular. If applied intramuscular then the application is made in two places, i.e., in the left and the right thigh. When applied intramuscular certain irritation may be felt, otherwise no other consequences may appear. The doses may be increased until 12 injection in the course of healing. All is worked slowly. The intervals may be longer, which depends on the case. In cases of internal purulent processes and inflamations with suppuration and inner pustule the application must be gradual because the inner pustule may close and form a scar, which may require an operation.

The standard combination of healing ingredient for human use is 200 mg of dry cysteine i.e., aminomercaptopropionic sodium salt, and 800 mg of dry disodium thiosulfate, both dissolved before injection in 10 ccm ditilled water per 24 hour period.

The standard combination of healing ingredients for animal use is stronger for big animals and the amount varies depending of the weight of animal. Thus, for each 50 kg net weight of animal 1 ccm of 100 mg of dry aminomercaptopropionic sodium salt, and 300 mg of dry disodium thiosulfate, both dissolved before injection in 1 ccm distilled water per 24 hour period.